| Long name: |
Biotin Conjugated, hydrogen exchanger 3 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
hydrogen exchanger 3 |
| Specificity: |
This is a highly specific antibody against hydrogen exchanger 3 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Subcellular location: |
Extracellular |
| Source: |
KLH conjugated synthetic peptide derived from human NHE3 |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
NHE-3 is also expressed in the stomach and functions to protect the mucosa by secreting protons that diffuse into the mucous cells, NHE-3 localizes to the apical membrane of renal proximal tubules where it is responsible for most of the sodium transport and fluid reabsorption, NHE-3 translocates to internal pools where it mediates natriuresis when blood pressure increases abruptly, NHEs mediate the transport of hydrogen (H+) ions out of cells in exchange for extracellular sodium (Na+) ions, While NHE-1 is ubiquitously expressed, the NHE isoforms 2-8 have distinct tissue- and cell type-dependent expression and inhibitory characteristics, where they regulate intracellular pH and cell volume, NHE-3 are integral membrane proteins that are expressed in most mammalian tissues |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
MGC126718, MGC126720, NHE 3, NHE-3, NHE3, SL9A3_HUMAN, SLC9A 3, Slc9a3, Sodium, Sodium/hydrogen exchanger, Sodium/hydrogen exchanger 3, Solute carrier family 9 member 3, Solute carrier family 9 sodium/hydrogen exchanger, Solute carrier family 9 sodium/hydrogen exchanger, apical epithelial, isoform 3, member 3, Na+/H+ exchanger 3 |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
hydrogen exchanger 3 Conjugated |
| Short name: |
Conjugated, hydrogen exchanger 3 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
biotinilated coupled, hydrogen exchanger 3 (Antibody to) |
| Alternative technique: |
antibodies |