| Long name: |
hydrogen exchanger 3 Primary Polyclonal Antibody |
| Also known as: |
hydrogen exchanger 3 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
hydrogen exchanger 3 |
| Specificity: |
This is a highly specific antibody against hydrogen exchanger 3 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Subcellular location: |
Extracellular |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human NHE3 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
NHE-3 is also expressed in the stomach and functions to protect the mucosa by secreting protons that diffuse into the mucous cells, NHE-3 localizes to the apical membrane of renal proximal tubules where it is responsible for most of the sodium transport and fluid reabsorption, NHE-3 translocates to internal pools where it mediates natriuresis when blood pressure increases abruptly, NHEs mediate the transport of hydrogen (H+) ions out of cells in exchange for extracellular sodium (Na+) ions, While NHE-1 is ubiquitously expressed, the NHE isoforms 2-8 have distinct tissue- and cell type-dependent expression and inhibitory characteristics, where they regulate intracellular pH and cell volume, NHE-3 are integral membrane proteins that are expressed in most mammalian tissues |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
MGC126718, MGC126720, NHE 3, NHE-3, NHE3, SL9A3_HUMAN, SLC9A 3, Slc9a3, Sodium, Sodium/hydrogen exchanger, Sodium/hydrogen exchanger 3, Solute carrier family 9 member 3, Solute carrier family 9 sodium/hydrogen exchanger, Solute carrier family 9 sodium/hydrogen exchanger, apical epithelial, isoform 3, member 3, Na+/H+ exchanger 3 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
hydrogen exchanger 3 |
| Short name: |
hydrogen exchanger 3 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
hydrogen exchanger 3 (Antibody to) |
| Alternative technique: |
antibodies |