| Long name: |
UBE2A Primary Polyclonal Antibody |
| Also known as: |
UBE2A PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
UBE2A |
| Specificity: |
This is a highly specific antibody against UBE2A |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human UBE2A/RAD6 |
| Gene ID number: |
7319 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
The Ub chain is then conjugated to the Ub-conjugating enzyme (E2) to generate an intermediate Ub-E2 complex, The Ub-ligase (E3) then catalyzes the transfer of Ub from E2 to the appropriate protein substrate, The first step requires the ATP-dependent activation of the Ub C-terminus and the assembly of multi-Ub chains by the Ub-activating enzyme known as the E1 component, UBE2A (Ubiquitin-conjugating enzyme E2 A) and UBE2B (Ubiquitin-conjugating enzyme E2 B) are both Ub-conjugating enzymes that are essential to postreplication repair of UV-damaged DNA, UBE2A and UBE2B are both nuclear and cell membrane proteins that have been found to interact with Rad18, The ubiquitin (Ub) pathway involves three sequential enzymatic steps that facilitate the conjugation of Ub and Ub-like molecules to specific protein substrates |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
HR6A, RAD6 homolog A, RAD6A, RAD6B, UBC-1, UBC2, UBC6, UBCD6, UBE2A, UBE2A_HUMAN, UBE2B, Ubiquitin carrier protein, Ubiquitin carrier protein A, Ubiquitin conjugating enzyme E2 17 kDa, Ubiquitin conjugating enzyme E2 21, Ubiquitin conjugating enzyme E2 A, Ubiquitin protein ligase A, Ubiquitin-conjugating enzyme E2 A, Ubiquitin-conjugating enzyme E2-17 kDa, Ubiquitin-conjugating enzyme E2-21, Ubiquitin-protein ligase A, hHR6A, mHR6A, 5 kDa, 5 kDa, BHR6A |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
UBE2A |
| Short name: |
UBE2A Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
UBE2A (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
12472 |
| Gene: |
UBE2A |
More about : UBE2A |
| Long gene name: |
ubiquitin conjugating enzyme E2 A |
| Synonyms gene name: |
ubiquitin-conjugating enzyme E2A (RAD6 homolog) ubiquitin-conjugating enzyme E2A |
| Synonyms: |
UBC2 HHR6A RAD6A |
| Locus: |
Xq24 |
| Discovery year: |
1992-12-02 |
| GenBank acession: |
AK223045 |
| Entrez gene record: |
7319 |
| Pubmed identfication: |
1559696 |
| RefSeq identity: |
NM_003336 |
| Classification: |
Ubiquitin conjugating enzymes E2 |
| Havana BLAST/BLAT: |
OTTHUMG00000022275 |
| Locus Specific Databases: |
Mental Retardation database |