| Long name: |
UBE2C Primary Polyclonal Antibody |
| Also known as: |
UBE2C PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
UBE2C |
| Specificity: |
This is a highly specific antibody against UBE2C |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human UBE2C |
| Gene ID number: |
11065 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
The Ub chain is then conjugated to the Ub-conjugating enzyme (E2) to generate an intermediate Ub-E2 complex, The Ub-ligase (E3) then catalyzes the transfer of Ub from E2 to the appropriate protein substrate, The first step requires the ATP-dependent activation of the Ub C-terminus and the assembly of multi-Ub chains by the Ub-activating enzyme known as the E1 component, UBE2C, UBE2C is overexpressed in many different types of cancers and may be a potential therapeutic target, also designated UBCH10 in human, is an E2 ubiquitin conjugating enzyme for the anaphase promoting complex (APC), which coordinates mitosis and G1 by sequentially promoting the degradation of key cell-cycle regulators, The ubiquitin (Ub) pathway involves three sequential enzymatic steps that facilitate the conjugation of Ub and Ub-like molecules to specific protein substrates |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
Mitotic specic ubiquitin conjugating enzyme, UB E2C, UBCH 10, UBCH10, UBE 2C, UBE2C_HUMAN, Ube2c, Ubiquitin carrier protein C, Ubiquitin carrier protein E2 C, Ubiquitin carrier protein E2C, Ubiquitin conjugating enzyme E2 C, Ubiquitin conjugating enzyme E2C, Ubiquitin protein ligase C, Ubiquitin-conjugating enzyme E2 C, Ubiquitin-protein ligase C, dJ447F3, 2, Cyclin selective ubiquitin carrier protein |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
UBE2C |
| Short name: |
UBE2C Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
UBE2C (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
15937 |
| Gene: |
UBE2C |
More about : UBE2C |
| Long gene name: |
ubiquitin conjugating enzyme E2 C |
| Synonyms gene name: |
ubiquitin-conjugating enzyme E2C |
| Synonyms: |
UBCH10 |
| Locus: |
20q13, 12 |
| Discovery year: |
2001-07-31 |
| GenBank acession: |
U73379 |
| Entrez gene record: |
11065 |
| Pubmed identfication: |
9122200 |
| RefSeq identity: |
NM_007019 |
| Classification: |
Ubiquitin conjugating enzymes E2 |
| Havana BLAST/BLAT: |
OTTHUMG00000033038 |