| Long name: |
FITC Conjugated, IKAROS Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
IKAROS |
| Specificity: |
This is a highly specific antibody against IKAROS |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human IKAROS |
| Gene ID number: |
10320 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
B- and T-cells, Binds and activates the enhancer (delta-A element) of the CD3-delta gene, Binds gamma-satellite DNA, Binds with higher affinity to gamma satellite A, Confers early temporal competence to retinal progenitor cells (RPCs), Increases normal apoptosis in adult erythroid cells, Lower expression in bone marrow and small intestine, NuRD and BAF (SWI/SNF), Plays a role in the development of lymphocytes, Regulates transcription through association with both HDAC-dependent and HDAC-independent complexes, Repressor of the TDT (terminal deoxynucleotidyltransferase) gene during thymocyte differentiation, Targets the 2 chromatin-remodeling complexes, in a single complex (PYR complex), spleen and peripheral blood Leukocytes and lymph nodes, to the beta-globin locus in adult erythrocytes, Tissue specificity:Abundantly expressed in thymus, Transcription regulator of hematopoietic cell differentiation |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
hIk-1 LyF-1 Hs, 54452 IKAROS PPP1R92 |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
IKAROS Conjugated |
| Short name: |
FITC Conjugated, IKAROS Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, IKAROS (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
13176 |
| Gene: |
IKZF1 |
More about : IKZF1 |
| Long gene name: |
IKAROS family zinc finger 1 |
| Synonyms gene: |
ZNFN1A1 |
| Synonyms gene name: |
1 (Ikaros) IKAROS family zinc finger 1 (Ikaros) , subfamily 1A, zinc finger protein |
| Synonyms name: |
protein phosphatase 1, regulatory subunit 92 |
| Locus: |
7p12, 2 |
| Discovery year: |
1999-08-23 |
| GenBank acession: |
U40462 |
| Entrez gene record: |
10320 |
| Pubmed identfication: |
1439790 7935426 |
| RefSeq identity: |
NM_006060 |
| Classification: |
Protein phosphatase 1 regulatory subunits Zinc fingers C2H2-type |
| Havana BLAST/BLAT: |
OTTHUMG00000155907 |