| Long name: |
IKAROS Primary Polyclonal Antibody |
| Also known as: |
IKAROS PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
IKAROS |
| Specificity: |
This is a highly specific antibody against IKAROS |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human IKAROS |
| Gene ID number: |
10320 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
B- and T-cells, Binds and activates the enhancer (delta-A element) of the CD3-delta gene, Binds gamma-satellite DNA, Binds with higher affinity to gamma satellite A, Confers early temporal competence to retinal progenitor cells (RPCs), Increases normal apoptosis in adult erythroid cells, Lower expression in bone marrow and small intestine, NuRD and BAF (SWI/SNF), Plays a role in the development of lymphocytes, Regulates transcription through association with both HDAC-dependent and HDAC-independent complexes, Repressor of the TDT (terminal deoxynucleotidyltransferase) gene during thymocyte differentiation, Targets the 2 chromatin-remodeling complexes, in a single complex (PYR complex), spleen and peripheral blood Leukocytes and lymph nodes, to the beta-globin locus in adult erythrocytes, Tissue specificity:Abundantly expressed in thymus, Transcription regulator of hematopoietic cell differentiation |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
CLL associated antigen KW 6, DNA-binding protein Ikaros, IK1, IKAROS, IKZF1_HUMAN, Ikaros family zinc finger protein 1, Ikaros zinc finger protein, Ikzf1, LYF1, Lymphoid transcription factor LyF-1, PRO0758, ZNFN1A1, hIk 1, hIk-1, zinc finger protein subfamily 1A 1, IKAROS family zinc finger 1 Ikaros |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
IKAROS |
| Short name: |
IKAROS Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
IKAROS (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
13176 |
| Gene: |
IKZF1 |
More about : IKZF1 |
| Long gene name: |
IKAROS family zinc finger 1 |
| Synonyms gene: |
ZNFN1A1 |
| Synonyms gene name: |
1 (Ikaros) IKAROS family zinc finger 1 (Ikaros) , subfamily 1A, zinc finger protein |
| Synonyms: |
hIk-1 LyF-1 Hs, 54452 IKAROS PPP1R92 |
| Synonyms name: |
protein phosphatase 1, regulatory subunit 92 |
| Locus: |
7p12, 2 |
| Discovery year: |
1999-08-23 |
| GenBank acession: |
U40462 |
| Entrez gene record: |
10320 |
| Pubmed identfication: |
1439790 7935426 |
| RefSeq identity: |
NM_006060 |
| Classification: |
Protein phosphatase 1 regulatory subunits Zinc fingers C2H2-type |
| Havana BLAST/BLAT: |
OTTHUMG00000155907 |