| Long name: |
FITC Conjugated, PPP2R1A Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
PPP2R1A |
| Specificity: |
This is a highly specific antibody against PPP2R1A |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human PPP2R1A |
| Gene ID number: |
5518 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
It consists of a common heteromeric core enzyme, The constant regulatory subunit alpha (PPP2R1A) serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory beta subunit, that associates with a variety of regulatory subunits, which is composed of a catalytic subunit and a constant regulatory subunit, Protein phosphatase 2A (PP2A) is the most abundant phosphatase specific for serine and threonine phosphorylation in mammalian cells |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
PR65A PP2A-Aalpha PP2AA |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
PPP2R1A Conjugated |
| Short name: |
FITC Conjugated, PPP2R1A Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
a (Antibody to), fluorecein coupled, regulatory functionnal sequence A, protein phosphatase 2 |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
DNA-templated and biological process this GO :0006461 and protein complex assembly and biological process this GO :0006470 and protein dephosphorylation and biological process this GO :0006672 and ceramide metabolic process and biological process this GO :0006915 and apoptotic process and biological process this GO :0007059 and chromosome segregation and biological process this GO :0007084 and mitotic nuclear envelope reassembly and biological process this GO :0008380 and RNA splicing and biological process this GO :0008543 and fibroblast growth factor receptor signaling pathway and biological process this GO :0008601 and protein phosphatase type 2A regulator activity and molecular function this GO :0010033 and response to organic substance and biological process this GO :0010467 and gene expression and biological process this GO :0015630 and microtubule cytoskeleton and cellular component this GO :0016020 and membrane and cellular component this GO :0016070 and RNA metabolic process and biological process this GO :0016071 and mRNA metabolic process and biological process this GO :0019932 and second-messenger-mediated signaling and biological process this GO :0030111 and regulation of Wnt signaling pathway and biological process this GO :0030155 and regulation of cell adhesion and biological process this GO :0030308 and negative regulation of cell growth and biological process this GO :0040008 and regulation of growth and biological process this GO :0042518 and negative regulation of tyrosine phosphorylation of Stat3 protein and biological process this GO :0045595 and regulation of cell differentiation and biological process this GO :0046982 and protein heterodimerization activity and molecular function this GO :0070262 and peptidyl-serine dephosphorylation and biological process this GO :2001241 and positive regulation of extrinsic apoptotic signaling pathway in absence of ligand and biological process, PP2A-Aalpha and PP2AAALPHA and PR65A, PPP2R1A and IDBG-641451 and ENSBTAG00000019851 and 535321, PPP2R1A and IDBG-66700 and ENSG00000105568 and 5518, Ppp2r1a and IDBG-141714 and ENSMUSG00000007564 and 51792, alpha, centromeric region and cellular component this GO :0003823 and antigen binding and molecular function this GO :0004722 and protein serine/threonine phosphatase activity and molecular function this GO :0005488 and binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005739 and mitochondrion and cellular component this GO :0005829 and cytosol and cellular component this GO :0006275 and regulation of DNA replication and biological process this GO :0006355 and regulation of transcription, nonsense-mediated decay and biological process this GO :0000188 and inactivation of MAPK activity and biological process this GO :0000278 and mitotic cell cycle and biological process this GO :0000775 and chromosome, nuclei, protein heterodimerization activity, regulatory subunit A, this GO :0000086 and G2/M transition of mitotic cell cycle and biological process this GO :0000159 and protein phosphatase type 2A complex and cellular component this GO :0000184 and nuclear-transcribed mRNA catabolic process, this GO :0003823 : antigen binding, this GO :0003823 : antigen binding and also this GO :0004722 : protein serine/threonine phosphatase activity and also this GO :0005488 : binding and also this GO :0005515 : protein binding and also this GO :0008601 : protein phosphatase type 2A regulator activity and also this GO :0046982 : protein heterodimerization activity, this GO :0004722 : protein serine/threonine phosphatase activity, this GO :0005488 : binding, this GO :0005515 : protein binding, this GO :0008601 : protein phosphatase type 2A regulator activity, this GO :0046982 : protein heterodimerization activity, protein phosphatase 2 |
| Identity: |
9302 |
| Gene: |
PPP2R1A |
More about : PPP2R1A |
| Long gene name: |
protein phosphatase 2 scaffold subunit Aalpha |
| Synonyms gene name: |
alpha isoform , protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65) |
| Synonyms name: |
65kDa regulatory subunit A protein phosphatase 2A structural subunit A, alpha isoform , alpha isoform protein phosphatase 2, protein phosphatase 2A, regulatory subunit A |
| Locus: |
19q13, 41 |
| Discovery year: |
1993-01-25 |
| Entrez gene record: |
5518 |
| RefSeq identity: |
NM_014225 |
| Classification: |
STRIPAK complex Protein phosphatase 2 scaffold subunits |
| Havana BLAST/BLAT: |
OTTHUMG00000137367 |