| Catalog number: | bs-7651R |
|---|---|
| Price: | 532 € |
| Supplier: | genways |
| Product name: | DNase I Antibody |
| Quantity: | 1 vial |
| Other quantities: | 1 vial 532€ |
| Related search: |
| Long name: | DNase I Primary Polyclonal Antibody |
|---|---|
| Also known as: | DNase I PAb |
| Category: | Primary Antibodies |
| Conjugation: | Unconjugated |
| Target Antigen: | DNase I |
| Specificity: | This is a highly specific antibody against DNase I |
| Modification(s): | None |
| Modification site(s): | Unmodified antibody |
| Clonality: | Polyclonal antibody |
| Clone number: | Polyclonal antibody |
| Concentration: | 1ug per 1ul |
| Source: | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human DNase I |
| Gene ID number: | 1773 |
| Tested Applications: | IF(IHC-P), IHC-P, WB |
| Recommended dilutions: | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: | Mouse, Rat, Human |
| Cross reactive species details: | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: | A DNase I-like enzyme appears to catalyze the degradation of chromatin to oligo- and mononucleosomes during apoptosis, A recent study has demonstrated an endonuclease with activity and antigenicity indistinguishable from DNase I in thymocytes, DNase I attacks each strand of DNA independently and the cleavage sites are random, DNase I is a Ca2+ and Mg2+ dependant endonuclease, DNase I is an endonuclease that hydrolyzes double-stranded or single stranded DNA preferentially at sites adjacent to pyrimidine nucleotides, DNase I is synthesized in the pancreas and stored in zymogen granules, In the form of a bovine pancreatic enzyme preparation, In the presence of Mg ion, It has been used to reduce the viscosity of cystic fibrosis sputum, The product of hydrolysis is a complex mixture of 5'-phosphate mononucleotides and oligonucleotides, and it was the first DNase for which a specific protein inhibitor was characterized, cells susceptible to apoptosis, it occupies an important place in the history of protein chemistry and enzymology: it was the first enzyme to be recognized as specific for DNA, it was the first DNase to be crystallized, 2 kb long with 9 exons separated by 8 introns, Deoxyribonuclease I gene is approximately 3 |
| Purification method: | This antibody was purified via Protein A |
| Storage conditions: | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: | DNAS1_HUMAN, DNASE 1, DNASE1, DNL 1, DNL1, DNase I lysosomal, DNaseI, DRNI, Deoxyribonuclease 1, Deoxyribonuclease I, Deoxyribonuclease1, DeoxyribonucleaseI, Dornase alfa, Human urine deoxyribonuclease I, RNASE1 |
| Properties: | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: | DNase I |
| Short name: | DNase I Antibody |
| Technique: | antibodies against human proteins, antibodies for, Antibody |
| Alternative name: | DNase I (Antibody to) |
| Alternative technique: | antibodies |
| Identity: | 2959 |
| Gene: | DNASE1L3 | More about : DNASE1L3 |
| Long gene name: | deoxyribonuclease 1 like 3 |
| Synonyms gene name: | deoxyribonuclease I like 3 |
| Synonyms: | DNAS1L3 LSD |
| Synonyms name: | DNase gamma |
| Locus: | 3p14, 3 |
| Discovery year: | 1997-05-15 |
| GenBank acession: | AF047354 |
| Entrez gene record: | 1776 |
| Pubmed identfication: | 9205125 9714828 14646506 |
| RefSeq identity: | NM_004944 |
| Havana BLAST/BLAT: | OTTHUMG00000159153 |
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