| Long name: |
Biotin Conjugated, RNF144B Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
RNF144B |
| Specificity: |
This is a highly specific antibody against RNF144B |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human IBRDC2/RING finger protein 144B |
| Gene ID number: |
255488 |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
But, However, Induces apoptosis via a p53/TP53-dependent but caspase-independent mechanism, a pro-apoptotic protein, and highest levels detectable in heart, it is not an anti-apoptotic protein per se, its overexpression also produces a decrease of the ubiquitin-dependent stability of BAX, ovary and testis, thereby promoting their degradation, ultimately leading to protection of cell death, with lowest levels in brain and thymus, E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes UBE2L3 and UBE2L6 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates such as LCMT2, Tissue specificity: Broadly expressed |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
bA528A10, 3 P53RFP |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
RNF144B Conjugated |
| Short name: |
Conjugated, RNF144B Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
biotinilated coupled, ring finger protein 144B (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
BT, Plasma membranes, RNF144B and IDBG-64050 and ENSG00000137393 and 255488, Rnf144b and IDBG-149475 and ENSMUSG00000038068 and 218215, ligase activity, this GO :0000151 and ubiquitin ligase complex and cellular component this GO :0004842 and ubiquitin-protein transferase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0006915 and apoptotic process and biological process this GO :0008270 and zinc ion binding and molecular function this GO :0016021 and integral component of membrane and cellular component this GO :0016874 and ligase activity and molecular function this GO :0031966 and mitochondrial membrane and cellular component this GO :0042787 and protein ubiquitination involved in ubiquitin-dependent protein catabolic process and biological process, this GO :0004842 : ubiquitin-protein transferase activity, this GO :0004842 : ubiquitin-protein transferase activity and also this GO :0005515 : protein binding and also this GO :0008270 : zinc ion binding and also this GO :0016874 : ligase activity, this GO :0005515 : protein binding, this GO :0008270 : zinc ion binding, this GO :0016874 : ligase activity, 66635 and IDBG-635837 and ENSBTAG00000009055 and 524166, ring finger protein 144B |
| Identity: |
21578 |
| Gene: |
RNF144B |
More about : RNF144B |
| Long gene name: |
ring finger protein 144B |
| Synonyms gene: |
IBRDC2 |
| Synonyms gene name: |
IBR domain containing 2 |
| Locus: |
6p22, 3 |
| Discovery year: |
2003-06-25 |
| GenBank acession: |
AK096832 |
| Entrez gene record: |
255488 |
| RefSeq identity: |
XM_172581 |
| Classification: |
Ring finger proteins RBR E3 ubiquitin ligases |
| Havana BLAST/BLAT: |
OTTHUMG00000014322 |