| Long name: |
CD45 Primary Polyclonal Antibody |
| Also known as: |
CD45 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
CD45 |
| Specificity: |
This is a highly specific antibody against CD45 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
475-525/806 |
| Subcellular location: |
Extracellular |
| Source: |
KLH conjugated synthetic peptide derived from Bovine CD45/B220 |
| Gene ID number: |
5788 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Bovine |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
180 kDa) which share a common large intracellular domain, 190, 205, CD45 is expressed on cells of the human hematopoietic lineage (including hematopoietic stem cells) with the exception of mature red cells, It is likely that CD45 plays an important role in signal transduction, It is not detected on differentiated cells of other tissues, The different isoforms are produced by alternative messenger RNA splicing of three exons of a single gene on chromosome 1, Their extracellular domains are heavily glycosylated, inhibition or upregulation of various immunological functions, recognising a common epitope on all of the isoforms are termed CD45 whilst those recognising only individual isoforms are termed CD45RA or CD45RO etc, CD45 is a family of single chain transmembraneous glycoproteins consisting of at least four isoforms (220 |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
C, CD 45, GP180, L CA, LCA, LY5, Leukocyte common antigen, PTPRC, Protein tyrosine phosphatase receptor type C, Protein tyrosine phosphatase receptor type c polypeptide, SCID due to PTPRC deficiency, T200, T200 glycoprotein, protein tyrosine phosphatase, receptor type, B220 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
CD45 |
| Short name: |
CD45 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
CD45 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
9666 |
| Gene: |
PTPRC |
More about : PTPRC |
| Long gene name: |
protein tyrosine phosphatase, receptor type C |
| Synonyms gene: |
CD45 |
| Synonyms: |
LCA T200 GP180 |
| Locus: |
1q31, 1 , 3-q32 |
| Discovery year: |
1986-01-01 |
| GenBank acession: |
Y00062 |
| Entrez gene record: |
5788 |
| Pubmed identfication: |
2169617 |
| RefSeq identity: |
NM_002838 |
| Classification: |
Fibronectin type III domain containing CD molecules Protein tyrosine phosphatases, receptor type |
| Havana BLAST/BLAT: |
OTTHUMG00000035702 |
| Locus Specific Databases: |
PTPRCbase: Mutation registry for CD45 deficiency LRG_95 |