| Long name: |
FITC Conjugated, ARHGEF18 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
ARHGEF18 |
| Specificity: |
This is a highly specific antibody against ARHGEF18 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human ARHGEF18/p114RhoGEF |
| Gene ID number: |
23370 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Activation of Rho GTPases is under the direct control of guanine nucleotide exchange factors (GEFs), Alternatively spliced transcript variants encoding different isoforms have been identified, Family members share a common feature, Oct 2008], The protein encoded by this gene is a guanine nucleotide exchange factor and belongs to the Rho GTPase GFE family, These cellular processes include cytoskeletal rearrangements, [provided by RefSeq, a Dbl (DH) homology domain followed by a pleckstrin (PH) homology domain, cell growth and motility, gene transcription, Rho GTPases are GTP binding proteins that regulate a wide spectrum of cellular functions |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
P114-RhoGEF KIAA0521 MGC15913 |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
ARHGEF18 Conjugated |
| Short name: |
FITC Conjugated, ARHGEF18 Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, Rho/Rac guanine nucleotide exchange factor (GEF) 18 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
ARHGEF18 and IDBG-22691 and ENSG00000104880 and 23370, Cell surfaces, Rho guanyl-nucleotide exchange factor activity, this GO :0005085 and guanyl-nucleotide exchange factor activity and molecular function this GO :0005089 and Rho guanyl-nucleotide exchange factor activity and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0007179 and transforming growth factor beta receptor signaling pathway and biological process this GO :0007264 and small GTPase mediated signal transduction and biological process this GO :0008360 and regulation of cell shape and biological process this GO :0030036 and actin cytoskeleton organization and biological process this GO :0030054 and cell junction and cellular component this GO :0032321 and positive regulation of Rho GTPase activity and biological process this GO :0035023 and regulation of Rho protein signal transduction and biological process this GO :0043065 and positive regulation of apoptotic process and biological process this GO :0043547 and positive regulation of GTPase activity and biological process this GO :0045177 and apical part of cell and cellular component this GO :0048011 and neurotrophin TRK receptor signaling pathway and biological process this GO :0051056 and regulation of small GTPase mediated signal transduction and biological process this GO :0097190 and apoptotic signaling pathway and biological process, this GO :0005085 : guanyl-nucleotide exchange factor activity, this GO :0005085 : guanyl-nucleotide exchange factor activity and also this GO :0005089 : Rho guanyl-nucleotide exchange factor activity, this GO :0005089 : Rho guanyl-nucleotide exchange factor activity, Rho/Rac guanine nucleotide exchange factor (GEF) 18 |
| Identity: |
17090 |
| Gene: |
ARHGEF18 |
More about : ARHGEF18 |
| Long gene name: |
Rho/Rac guanine nucleotide exchange factor 18 |
| Synonyms gene name: |
rho/rac guanine nucleotide exchange factor (GEF) 18 Rho/Rac guanine nucleotide exchange factor (GEF) 18 |
| Synonyms name: |
Rho-specific guanine nucleotide exchange factor p114 |
| Locus: |
19p13, 2 |
| Discovery year: |
2004-01-09 |
| GenBank acession: |
AK074372 |
| Entrez gene record: |
23370 |
| Pubmed identfication: |
9628581 11318610 |
| RefSeq identity: |
NM_015318 |
| Classification: |
Rho guanine nucleotide exchange factors Pleckstrin homology domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000177342 |