| Long name: |
Cy5, 5 Conjugated, DOCK1 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Cy5, 5, 5, Cy5 |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
DOCK1 |
| Specificity: |
This is a highly specific antibody against DOCK1 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human DOCK1 |
| Gene ID number: |
1793 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Expressed at intermediate level in thymus, Functions as a guanine nucleotide exchange factor (GEF), Its GEF activity may be enhanced by ELMO1, kidney, lung, pancreas and ovary, testes and colon, which activates Rac Rho small GTPases by exchanging bound GDP for free GTP, Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility, Tissue specificity: Highly expressed in placenta |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
675nm/694nm |
| Synonyms: |
DOCK180 ced5 |
| Properties: |
Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Conjugated: |
These antibodies are excite for emission at 678nm and detected at a 694 , nm wavelengths |
| Gene target: |
DOCK1 Conjugated |
| Short name: |
Conjugated, DOCK1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
5, Cy5 |
| Alternative name: |
cyanine 5, 5 coupled, dedicator on cytokinesis 1 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
DOCK1 and IDBG-640952 and ENSBTAG00000031890 and 537203, DOCK1 and IDBG-93118 and ENSG00000150760 and 1793, Dock1 and IDBG-211315 and ENSMUSG00000058325 and 330662, ced5 and DOCK180, engulfment and biological process this GO :0006915 and apoptotic process and biological process this GO :0007165 and signal transduction and biological process this GO :0007229 and integrin-mediated signaling pathway and biological process this GO :0007264 and small GTPase mediated signal transduction and biological process this GO :0007411 and axon guidance and biological process this GO :0007596 and blood coagulation and biological process this GO :0009055 and electron carrier activity and molecular function this GO :0016020 and membrane and cellular component this GO :0016477 and cell migration and biological process this GO :0017124 and SH3 domain binding and molecular function this GO :0020037 and heme binding and molecular function this GO :0038096 and Fc-gamma receptor signaling pathway involved in pha this GO cytosis and biological process this GO :0043547 and positive regulation of GTPase activity and biological process this GO :0045087 and innate immune response and biological process, heme binding, nuclei, this GO :0002244 and hematopoietic progenitor cell differentiation and biological process this GO :0005085 and guanyl-nucleotide exchange factor activity and molecular function this GO :0005096 and GTPase activator activity and molecular function this GO :0005488 and binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0006911 and pha this GO cytosis, this GO :0005085 : guanyl-nucleotide exchange factor activity, this GO :0005085 : guanyl-nucleotide exchange factor activity and also this GO :0005096 : GTPase activator activity and also this GO :0005488 : binding and also this GO :0005515 : protein binding and also this GO :0009055 : electron carrier activity and also this GO :0017124 : SH3 domain binding and also this GO :0020037 : heme binding, this GO :0005096 : GTPase activator activity, this GO :0005488 : binding, this GO :0005515 : protein binding, this GO :0009055 : electron carrier activity, this GO :0017124 : SH3 domain binding, this GO :0020037 : heme binding, dedicator of cytokinesis 1 |
| Identity: |
2987 |
| Gene: |
DOCK1 |
More about : DOCK1 |
| Long gene name: |
dedicator of cytokinesis 1 |
| Synonyms gene name: |
dedicator of cyto-kinesis 1 |
| Synonyms name: |
DOwnstream of CrK |
| Locus: |
10q26, 2 |
| Discovery year: |
1998-05-13 |
| GenBank acession: |
D50857 |
| Entrez gene record: |
1793 |
| Pubmed identfication: |
8657152 8661160 |
| RefSeq identity: |
NM_001380 |
| Havana BLAST/BLAT: |
OTTHUMG00000019249 |