| Long name: |
Biotin Conjugated, PARP3 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
PARP3 |
| Specificity: |
This is a highly specific antibody against PARP3 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human PARP3 |
| Gene ID number: |
10039 |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Binds DNA, May be involved in the regulation of PRC2 and PRC3 complex-dependent gene silencing, May link the DNA damage surveillance network to the mitotic fidelity checkpoint, Negatively influences the G1/S cell cycle progression without interfering with centrosome duplication, This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks, also detected in pancreas, brain, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism, colon, heart and spleen, leukocytes, liver, lung, ovary, placenta, prostate and thymus, skeletal muscle, small intestine, testis, the highest levels are in the kidney, Involved in the base excision repair (BER) pathway, Tissue specificity: Widely expressed |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
ADPRT3 IRT1 hPARP-3 pADPRT-3 |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
PARP3 Conjugated |
| Short name: |
Conjugated, PARP3 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
biotinilated coupled, PARP3 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
273 |
| Gene: |
PARP3 |
More about : PARP3 |
| Long gene name: |
poly(ADP-ribose) polymerase family member 3 |
| Synonyms gene: |
ADPRTL3 |
| Synonyms gene name: |
ADP-ribosyltransferase (NAD+, poly (ADP-ribose) polymerase)-like 3 |
| Synonyms name: |
poly(ADP-ribose) synthetase-3 NAD+ ADP-ribosyltransferase 3 poly(ADP-ribose) polymerase 3 |
| Locus: |
3p21, 2 |
| Discovery year: |
1999-05-24 |
| GenBank acession: |
AF083068 |
| Entrez gene record: |
10039 |
| Pubmed identfication: |
10329013 |
| RefSeq identity: |
NM_005485, 4 |
| Classification: |
Poly(ADP-ribose) polymerases |
| Havana BLAST/BLAT: |
OTTHUMG00000156931 |