| Long name: |
ALEXA FLUOR 350 Conjugated, PARP3 Polyclonal Antibody |
| Also known as: |
Anti-PARP3 PAb ALEXA FLUOR 350 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
350, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
PARP3 |
| Specificity: |
This is a highly specific antibody against PARP3 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human PARP3 |
| Gene ID Number: |
10039 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Binds DNA, May be involved in the regulation of PRC2 and PRC3 complex-dependent gene silencing, May link the DNA damage surveillance network to the mitotic fidelity checkpoint, Negatively influences the G1/S cell cycle progression without interfering with centrosome duplication, This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks, also detected in pancreas, brain, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism, colon, heart and spleen, leukocytes, liver, lung, ovary, placenta, prostate and thymus, skeletal muscle, small intestine, testis, the highest levels are in the kidney, Involved in the base excision repair (BER) pathway, Tissue specificity: Widely expressed |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
343nm/442nm |
| Synonyms: |
ADPRT3 IRT1 hPARP-3 pADPRT-3 |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 350, Alexa Fluor |
| Gene target: |
PARP3 |
| Short name: |
PARP3 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 350 |
| Alternative name: |
ALEXA FLUOR 350, PARP3 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
273 |
| Gene: |
PARP3 |
More about : PARP3 |
| Long gene name: |
poly(ADP-ribose) polymerase family member 3 |
| Synonyms gene: |
ADPRTL3 |
| Synonyms gene name: |
ADP-ribosyltransferase (NAD+, poly (ADP-ribose) polymerase)-like 3 |
| Synonyms name: |
poly(ADP-ribose) synthetase-3 NAD+ ADP-ribosyltransferase 3 poly(ADP-ribose) polymerase 3 |
| Locus: |
3p21, 2 |
| Discovery year: |
1999-05-24 |
| GenBank acession: |
AF083068 |
| Entrez gene record: |
10039 |
| Pubmed identfication: |
10329013 |
| RefSeq identity: |
NM_005485, 4 |
| Classification: |
Poly(ADP-ribose) polymerases |
| Havana BLAST/BLAT: |
OTTHUMG00000156931 |