| Long name: |
PARP3 Primary Polyclonal Antibody |
| Also known as: |
PARP3 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
PARP3 |
| Specificity: |
This is a highly specific antibody against PARP3 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human PARP3 |
| Gene ID number: |
10039 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Binds DNA, May be involved in the regulation of PRC2 and PRC3 complex-dependent gene silencing, May link the DNA damage surveillance network to the mitotic fidelity checkpoint, Negatively influences the G1/S cell cycle progression without interfering with centrosome duplication, This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks, also detected in pancreas, brain, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism, colon, heart and spleen, leukocytes, liver, lung, ovary, placenta, prostate and thymus, skeletal muscle, small intestine, testis, the highest levels are in the kidney, Involved in the base excision repair (BER) pathway, Tissue specificity: Widely expressed |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
ADP ribosyltransferase NAD+, ADPRT-3, ADPRT3, ADPRTL2, ADPRTL3, IRT 1, IRT1, IRT1, NAD+ ADP ribosyltransferase 3, NAD+ ADP ribosyltransferase 3, NAD+ ADP-ribosyltransferase 3, PARP 3, PARP-3, PARP3, Poly ADP ribose polymerase family, Poly ADP ribose synthetase 3, Poly [ADP-ribose] polymerase 3, Poly[ADP ribose] synthetase 3, Poly[ADP-ribose] synthase 3, hPARP 3, hPARP-3, member 3, pADPRT 3, pADPRT-3, pADPRT3, poly ADP ribose, hPARP3 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
PARP3 |
| Short name: |
PARP3 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
PARP3 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
273 |
| Gene: |
PARP3 |
More about : PARP3 |
| Long gene name: |
poly(ADP-ribose) polymerase family member 3 |
| Synonyms gene: |
ADPRTL3 |
| Synonyms gene name: |
ADP-ribosyltransferase (NAD+, poly (ADP-ribose) polymerase)-like 3 |
| Synonyms: |
ADPRT3 IRT1 hPARP-3 pADPRT-3 |
| Synonyms name: |
poly(ADP-ribose) synthetase-3 NAD+ ADP-ribosyltransferase 3 poly(ADP-ribose) polymerase 3 |
| Locus: |
3p21, 2 |
| Discovery year: |
1999-05-24 |
| GenBank acession: |
AF083068 |
| Entrez gene record: |
10039 |
| Pubmed identfication: |
10329013 |
| RefSeq identity: |
NM_005485, 4 |
| Classification: |
Poly(ADP-ribose) polymerases |
| Havana BLAST/BLAT: |
OTTHUMG00000156931 |