| Long name: |
SRGN Primary Polyclonal Antibody |
| Also known as: |
SRGN PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
SRGN |
| Specificity: |
This is a highly specific antibody against SRGN |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Serglycin/SRGN Polyclonal Antibody |
| Gene ID number: |
5552 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Inhibits bone mineralization, Mediates processing of MMP2, Plays a role in cytotoxic cell granule-mediated apoptosis by forming a complex with granzyme B which is delivered to cells by perforin to induce apoptosis, Plays a role in localizing neutrophil elastase in azurophil granules of neutrophils, Regulates the secretion of TNF-alpha and may also regulate protease secretion, Required for storage of some proteases in both connective tissue and mucosal mast cells and for storage of granzyme B in T lymphocytes, Plays a role in formation of mast cell secretory granules and mediates storage of various compounds in secretory vesicles |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
Cytolytic granule proteoglycan core protein, Hematopoetic proteoglycan core protein, Mastocytoma proteoglycan core protein, P, PG19 core protein, PLATELET PROTEOGLYCAN PROTEIN CORE, PPG, PRG, PRG1, PROTEOGLYCAN 1, PROTEOGLYCAN PROTEIN CORE FOR MAST CELL SECRETORY GRANULE, Pgsg, Platelet proteoglycan core protein, Proteoglycan 10K core protein, Proteoglycan peptide core protein, SRGN_HUMAN, Secretory granule proteoglycan core protein, Serglycin, Sgc, Srgn, platelet proteoglycan protein core, proteoglycan 1, secretory granule, secretory granule proteoglycan 1, serglycin proteoglycan, Chondroitin sulfate proteoglycan core protein, PG |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
SRGN |
| Short name: |
SRGN Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
serglycin (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
BT, Extracellular, PPG and PRG and PRG1, SRGN and IDBG-76481 and ENSG00000122862 and 5552, Srgn and IDBG-157635 and ENSMUSG00000020077 and 19073, collagen binding, this GO :0000139 and this GO lgi membrane and cellular component this GO :0002576 and platelet degranulation and biological process this GO :0005515 and protein binding and molecular function this GO :0005518 and collagen binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005615 and extracellular space and cellular component this GO :0005794 and this GO lgi apparatus and cellular component this GO :0007596 and blood coagulation and biological process this GO :0008626 and granzyme-mediated apoptotic signaling pathway and biological process this GO :0016485 and protein processing and biological process this GO :0030168 and platelet activation and biological process this GO :0030502 and negative regulation of bone mineralization and biological process this GO :0031093 and platelet alpha granule lumen and cellular component this GO :0031214 and biomineral tissue development and biological process this GO :0033364 and mast cell secretory granule organization and biological process this GO :0033371 and T cell secretory granule organization and biological process this GO :0033373 and maintenance of protease location in mast cell secretory granule and biological process this GO :0033382 and maintenance of granzyme B location in T cell secretory granule and biological process this GO :0042588 and zymogen granule and cellular component this GO :0042629 and mast cell granule and cellular component this GO :0050710 and negative regulation of cytokine secretion and biological process, this GO :0005515 : protein binding, this GO :0005515 : protein binding and also this GO :0005518 : collagen binding, this GO :0005518 : collagen binding, 97928 and IDBG-629459 and ENSBTAG00000017863 and 509501, serglycin |
| Identity: |
9361 |
| Gene: |
SRGN |
More about : SRGN |
| Long gene name: |
serglycin |
| Synonyms gene: |
PRG PRG1 |
| Synonyms gene name: |
proteoglycan 1, secretory granule |
| Synonyms: |
PPG |
| Synonyms name: |
serglycin proteoglycan |
| Locus: |
10q22, 1 |
| Discovery year: |
1988-07-22 |
| GenBank acession: |
BC015516 |
| Entrez gene record: |
5552 |
| RefSeq identity: |
NM_002727 |
| Classification: |
Proteoglycans |
| Havana BLAST/BLAT: |
OTTHUMG00000018369 |