| Long name: |
ALEXA FLUOR 555 Conjugated, ID4 Polyclonal Antibody |
| Also known as: |
Anti-ID4 PAb ALEXA FLUOR 555 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
555, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
ID4 |
| Specificity: |
This is a highly specific antibody against ID4 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human ID4 |
| Gene ID Number: |
3400 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Due to the absence of the basic region, Id2 (4), Id3 and Id4 (5), It has been shown that expression of each of the Id proteins is strongly dependent on growth factor activation and that reduction of Id mRNA levels by antisense oligonucleotides leads to a delayed reentry of arrested cells into the cell cycle following growth factor stimulation, Since Id1 inhibits DNA binding of E12 and Myo D, The Id-type proteins thus appear to negatively regulate DNA binding of bHLH proteins, They are ubiquitously expressed and dimerize with members of the class A and B HLH proteins (1â, Under conditions that facilitate muscle cell differentiation, allowing E12 and/or E47 to form heterodimers with Myo D and myogenin, it apparently functions to inhibit muscle-specific gene expression, the Id protein levels fall, the resulting heterodimers cannot bind DNA, which in turn activate myogenic differentiation, &euro, &euro, &ldquo, &ldquo, 3), 5), Members of the Id family of basic helix-loop-helix (bHLH) proteins include Id1 (1â |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
553nm/568nm |
| Synonyms: |
bHLHb27 |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, Very high photo stable ALEXA conjugate, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 555, Alexa Fluor |
| Gene target: |
ID4 |
| Short name: |
ID4 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 555 |
| Alternative name: |
ALEXA FLUOR 555, ID4 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
5363 |
| Gene: |
ID4 |
More about : ID4 |
| Long gene name: |
HLH protein , inhibitor of DNA binding 4 |
| Synonyms gene name: |
dominant negative helix-loop-helix protein , inhibitor of DNA binding 4 |
| Synonyms name: |
inhibitor of differentiation 4 |
| Locus: |
6p22, 3 |
| Discovery year: |
1995-02-13 |
| GenBank acession: |
U16153 |
| Entrez gene record: |
3400 |
| Pubmed identfication: |
7665172 |
| RefSeq identity: |
NM_001546 |
| Classification: |
Basic helix-loop-helix proteins |
| Havana BLAST/BLAT: |
OTTHUMG00000014333 |