| Long name: |
ALEXA FLUOR 350 Conjugated, TYK2 Polyclonal Antibody |
| Also known as: |
Anti-TYK2 PAb ALEXA FLUOR 350 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
350, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
TYK2 |
| Specificity: |
This is a highly specific antibody against TYK2 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human TYK2 |
| Gene ID Number: |
7297 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E, As such, It is also component of both the type I and type III interferon signaling pathways, This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits, [provided by RefSeq], it may play a role in anti-viral immunity, more specifically, the Janus kinases (JAKs) protein families, This gene encodes a member of the tyrosine kinase and |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
343nm/442nm |
| Synonyms: |
JTK1 |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 350, Alexa Fluor |
| Gene target: |
TYK2 |
| Short name: |
TYK2 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 350 |
| Alternative name: |
ALEXA FLUOR 350, tyrosine kinase 2 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
BT, IMD35 and JTK1, TYK2 and IDBG-27182 and ENSG00000105397 and 7297, Tyk2 and IDBG-139044 and ENSMUSG00000032175 and 54721, nuclei, this GO :0004672 and protein kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0004715 and non-membrane spanning protein tyrosine kinase activity and molecular function this GO :0005131 and growth hormone receptor binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0005856 and cytoskeleton and cellular component this GO :0006468 and protein phosphorylation and biological process this GO :0016020 and membrane and cellular component this GO :0016772 and transferase activity, this GO :0004672 : protein kinase activity, this GO :0004672 : protein kinase activity and also this GO :0004713 : protein tyrosine kinase activity and also this GO :0004715 : non-membrane spanning protein tyrosine kinase activity and also this GO :0005131 : growth hormone receptor binding and also this GO :0005515 : protein binding and also this GO :0005524 : ATP binding and also this GO :0016772 : transferase activity, this GO :0004713 : protein tyrosine kinase activity, this GO :0004715 : non-membrane spanning protein tyrosine kinase activity, this GO :0005131 : growth hormone receptor binding, this GO :0005515 : protein binding, this GO :0005524 : ATP binding, this GO :0016772 : transferase activity, this GO :0031702 : type 1 angiotensin receptor binding, transferase activity, transferring phosphorus-containing groups, transferring phosphorus-containing groups and also this GO :0031702 : type 1 angiotensin receptor binding, transferring phosphorus-containing groups and molecular function this GO :0018108 and peptidyl-tyrosine phosphorylation and biological process this GO :0019221 and cytokine-mediated signaling pathway and biological process this GO :0031702 and type 1 angiotensin receptor binding and molecular function this GO :0035556 and intracellular signal transduction and biological process this GO :0045087 and innate immune response and biological process this GO :0060337 and type I interferon signaling pathway and biological process this GO :0060338 and regulation of type I interferon-mediated signaling pathway and biological process this GO :0070062 and extracellular vesicular exosome and cellular component, 23803 and IDBG-643269 and ENSBTAG00000011698 and 512484, tyrosine kinase 2 |
| Identity: |
12440 |
| Gene: |
TYK2 |
More about : TYK2 |
| Long gene name: |
tyrosine kinase 2 |
| Locus: |
19p13, 2 |
| Discovery year: |
1990-09-10 |
| Entrez gene record: |
7297 |
| Pubmed identfication: |
2156206 |
| Classification: |
FERM domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000166373 |
| Locus Specific Databases: |
TYK2base: Mutation registry for TYK2 deficiency LRG_121 |