| Long name: |
Biotin Conjugated, CD98 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
CD98 |
| Specificity: |
This is a highly specific antibody against CD98 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
257-280/630 |
| Subcellular location: |
Extracellular |
| Source: |
KLH conjugated synthetic peptide derived from human CD98 |
| Gene ID number: |
6520 |
| Swiss Prot: |
P08195 |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Involved in guiding and targeting of LAT1 and LAT2 to the plasma membrane, Involved in sodium-independent, Involved in the uptake of methylmercury (MeHg) when administered as the L-cysteine or D, Plays a role in nitric oxide synthesis in human umbilical vein endothelial cells (HUVECs) via transport of L-arginine, Required for normal and neoplastic cell growth, Together with ICAM1, When associated with SLC7A5, When associated with SLC7A5 or SLC7A8, When associated with SLC7A5/LAT1, When associated with SLC7A6 or SLC7A7 acts as an arginine/glutamine exchanger, and hence plays a role in metal ion homeostasis and toxicity, and that of thyroid hormones triiodothyronine (T3) and thyroxine (T4) across the cell membrane in tissues such as placenta, arginine and tryptophan, by generating and delivering intracellular signals, following an antiport mechanism for amino acid transport, high-affinity transport of large neutral amino acids such as phenylalanine, influencing arginine release in exchange for extracellular amino acids, involved in the cellular activity of small molecular weight nitrosothiols, is also involved in the transport of L-DOPA across the blood-brain barrier, leucine, plays an important role in transporting L-leucine from the circulating blood to the retina across the inner blood-retinal barrier, regulates the transport activity LAT2 in polarized intestinal cells, tyrosine, via the stereoselective transport of L-nitrosocysteine (L-CNSO) across the transmembrane, L-homocysteine complexes, Required for the function of light chain amino-acid transporters |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
LAT1 E16 D16S469E MPE16 CD98 |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
CD98 Conjugated |
| Short name: |
Conjugated, CD98 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
biotinilated coupled, CD98 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
11063 |
| Gene: |
SLC7A5 |
More about : SLC7A5 |
| Long gene name: |
solute carrier family 7 member 5 |
| Synonyms gene name: |
L system), member 5 , solute carrier family 7 (amino acid transporter light chain |
| Locus: |
16q24, 2 |
| Discovery year: |
1999-01-28 |
| GenBank acession: |
AF077866 |
| Entrez gene record: |
8140 |
| Pubmed identfication: |
9751058 7829099 |
| RefSeq identity: |
NM_003486 |
| Classification: |
Solute carriers CD molecules |
| Havana BLAST/BLAT: |
OTTHUMG00000137658 |