| Long name: |
ALEXA FLUOR 350 Conjugated, TLR7 Polyclonal Antibody |
| Also known as: |
Anti-TLR7 PAb ALEXA FLUOR 350 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
350, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
TLR7 |
| Specificity: |
This is a highly specific antibody against TLR7 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
500-550/1049 |
| Subcellular location: |
Intracellular |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human TLR7 |
| Gene ID Number: |
51284 |
| Swiss Prot: |
Q9NYK1 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Acts via MYD88 and TRAF6, TLR7 is a nucleotide-sensing TLR which is activated by single-stranded RNA, TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms, cytokine secretion and the inflammatory response (By similarity), leading to NF-kappa-B activation, Key component of innate and adaptive immunity |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
343nm/442nm |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 350, Alexa Fluor |
| Gene target: |
TLR7 |
| Short name: |
TLR7 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 350 |
| Alternative name: |
ALEXA FLUOR 350, toll-like receptor 7 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
Plasma membranes, TLR7 and IDBG-44230 and ENSG00000196664 and 51284, TLR7 and IDBG-639302 and ENSBTAG00000022161 and 493686, Tlr7 and IDBG-185532 and ENSMUSG00000044583 and 170743, siRNA binding, this GO :0000139 and this GO lgi membrane and cellular component this GO :0001774 and microglial cell activation and biological process this GO :0002224 and toll-like receptor signaling pathway and biological process this GO :0002755 and MyD88-dependent toll-like receptor signaling pathway and biological process this GO :0003725 and double-stranded RNA binding and molecular function this GO :0003727 and single-stranded RNA binding and molecular function this GO :0004888 and transmembrane signaling receptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0005764 and lysosome and cellular component this GO :0005768 and endosome and cellular component this GO :0005783 and endoplasmic reticulum and cellular component this GO :0005789 and endoplasmic reticulum membrane and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006954 and inflammatory response and biological process this GO :0007165 and signal transduction and biological process this GO :0007252 and I-kappaB phosphorylation and biological process this GO :0008144 and drug binding and molecular function this GO :0010008 and endosome membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0032009 and early pha this GO some and cellular component this GO :0032722 and positive regulation of chemokine production and biological process this GO :0032755 and positive regulation of interleukin-6 production and biological process this GO :0032757 and positive regulation of interleukin-8 production and biological process this GO :0034154 and toll-like receptor 7 signaling pathway and biological process this GO :0034162 and toll-like receptor 9 signaling pathway and biological process this GO :0035197 and siRNA binding and molecular function this GO :0036020 and endolysosome membrane and cellular component this GO :0042346 and positive regulation of NF-kappaB import into nucleus and biological process this GO :0043235 and receptor complex and cellular component this GO :0045078 and positive regulation of interferon-gamma biosynthetic process and biological process this GO :0045087 and innate immune response and biological process this GO :0045356 and positive regulation of interferon-alpha biosynthetic process and biological process this GO :0045359 and positive regulation of interferon-beta biosynthetic process and biological process this GO :0045416 and positive regulation of interleukin-8 biosynthetic process and biological process this GO :0050729 and positive regulation of inflammatory response and biological process this GO :0051607 and defense response to virus and biological process this GO :0071260 and cellular response to mechanical stimulus and biological process, this GO :0003725 : double-stranded RNA binding, this GO :0003725 : double-stranded RNA binding and also this GO :0003727 : single-stranded RNA binding and also this GO :0004888 : transmembrane signaling receptor activity and also this GO :0005515 : protein binding and also this GO :0008144 : drug binding and also this GO :0035197 : siRNA binding, this GO :0003727 : single-stranded RNA binding, this GO :0004888 : transmembrane signaling receptor activity, this GO :0005515 : protein binding, this GO :0008144 : drug binding, this GO :0035197 : siRNA binding, toll-like receptor 7 |
| Identity: |
15631 |
| Gene: |
TLR7 |
More about : TLR7 |
| Long gene name: |
toll like receptor 7 |
| Synonyms gene name: |
toll-like receptor 7 |
| Locus: |
Xp22, 2 |
| Discovery year: |
2001-04-27 |
| GenBank acession: |
AF240467 |
| Entrez gene record: |
51284 |
| Pubmed identfication: |
11022119 |
| RefSeq identity: |
NM_016562 |
| Classification: |
Toll like receptors |
| Havana BLAST/BLAT: |
OTTHUMG00000021137 |
| Locus Specific Databases: |
Mental Retardation database |