| Long name: |
Recombinant Human GDNF family receptor alpha-2 (GFRA2) |
| Alternative names: |
GDNF family receptor alpha 2, GDNF family receptor alpha-2, GDNF family receptor alpha-2, GDNF receptor beta, GDNF receptor beta, GDNFR-alpha-2, GDNFR-beta, GDNFR-beta, GFR-alpha 2, GPI-anchored, NRTNR-alpha, NTNR-alpha, NTNR-alpha, Neurturin receptor alpha, PI-linked cell-surface accessory protein, RET ligand 2, RET ligand 2, TGF-beta-related neurotrophic factor receptor 2, TGF-beta-related neurotrophic factor receptor 2, TRN receptor, beta, glial cell line derived neurotrophic factor receptor, neurturin receptor alpha, GDNF family receptor alpha-2 isoform b |
| Gene name: |
GFRA2 |
| Other gene names: |
GDNF receptor alpha-2, GDNFR-alpha-2, GDNFR-beta, GDNFRB, GDNFRB, GFR-alpha-2, GFRA2, NRTNR-ALPHA, NRTNR-alpha, NTNR-alpha, NTNRA, RETL2, RETL2, TRNR2, TRNR2, GFRA2 |
| General description: |
All of our recombinant proteins are manufactured in strictly controlled facilities and by using a well established technology which guarantees full batch-to-bact consistency and experiment reproducibility, The protein can be with or without a His-Tag or other tag in accordance to customer's request, GDNF family receptor alpha-2(GFRA2) is a recombinant protein expressed in Yeast |
| Product category: |
Recombinant Proteins |
| Expression system: |
Yeast |
| Available also expressed in:: |
Baculovirus , Mammalian Cell, Yeast , E Coli |
| Purity: |
Greater than 90% (determined by SDS-PAGE) |
| Form: |
Lyophilized protein |
| Storage: |
Avoid cycles of freezing and thawing as they might denaturate the polypeptide chains, For extended periods of time it is recommended to keep the protein frozen at -40 or -80 degrees Celsius, This protein can be stored at -20 degrees Celsius |
| Applications: |
IFA, RIA, Western Blot, etc, This protein can be used as a positive control for applications such as ELISA |
| Properties: |
Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine,  , (Homo sapiens, Homo sapiens sapiens), Human proteins, humans , ssp |
| Description: |
2 or 3 and , However, In this sense, When such chemical-signals couple or bind to a receptor, a change in the electrical-activity of a cell, acetylcholine, am olfactory receptor is a protein-molecule that recognizes and responds to , an acetylcholine-receptor recognizes and responds to its endogenous-ligand, chemokinesor cytokines e, e, sometimes in pharmacology, such as enzymes, the term is also used to include other proteins that are drug-targets, they cause some form of cellular/tissue-response, transporters and ion-channels, The receptors are ligand binding factors of type 1, endogenous-chemical signals, g, g, protein-molecules , that receive chemical-signals from outside a cell |
| Gene target: |
GDNF family receptor alpha-2 (GFRA2) |
| Short name: |
GDNF family receptor alpha-2 (GFRA2) |
| Species: |
Humans, Human |
| Alternative name: |
sapiens glial cell derived neurotrophic factor family receptor a-2 (GFRA2), H |
| Alternative to gene target: |
ATF1 and ATF2 and HFB1-GDNF and HSCR3, BT, Extracellular, GDNF and IDBG-17169 and ENSG00000168621 and 2668, Gdnf and IDBG-128378 and ENSMUSG00000022144 and 14573, protein homodimerization activity, this GO :0001656 and metanephros development and biological process this GO :0001657 and ureteric bud development and biological process this GO :0001658 and branching involved in ureteric bud morphogenesis and biological process this GO :0001755 and neural crest cell migration and biological process this GO :0001759 and organ induction and biological process this GO :0001941 and postsynaptic membrane organization and biological process this GO :0003337 and mesenchymal to epithelial transition involved in metanephros morphogenesis and biological process this GO :0005102 and receptor binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0007165 and signal transduction and biological process this GO :0007399 and nervous system development and biological process this GO :0007411 and axon guidance and biological process this GO :0007422 and peripheral nervous system development and biological process this GO :0008083 and growth factor activity and molecular function this GO :0008344 and adult locomotory behavior and biological process this GO :0021784 and postganglionic parasympathetic nervous system development and biological process this GO :0030432 and peristalsis and biological process this GO :0031175 and neuron projection development and biological process this GO :0032770 and positive regulation of monooxygenase activity and biological process this GO :0033603 and positive regulation of dopamine secretion and biological process this GO :0042803 and protein homodimerization activity and molecular function this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043524 and negative regulation of neuron apoptotic process and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0048255 and mRNA stabilization and biological process this GO :0048484 and enteric nervous system development and biological process this GO :0048485 and sympathetic nervous system development and biological process this GO :0051584 and regulation of dopamine uptake involved in synaptic transmission and biological process this GO :0060676 and ureteric bud formation and biological process this GO :0060688 and regulation of morphogenesis of a branching structure and biological process this GO :0072107 and positive regulation of ureteric bud formation and biological process this GO :0072108 and positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis and biological process this GO :0090190 and positive regulation of branching involved in ureteric bud morphogenesis and biological process this GO :2001240 and negative regulation of extrinsic apoptotic signaling pathway in absence of ligand and biological process, this GO :0005102 : receptor binding, this GO :0005102 : receptor binding and also this GO :0008083 : growth factor activity and also this GO :0042803 : protein homodimerization activity, this GO :0008083 : growth factor activity, this GO :0042803 : protein homodimerization activity, 58072 and IDBG-630047 and ENSBTAG00000005176 and 386587, glial cell derived neurotrophic factor |
| Identity: |
4244 |
| Gene: |
GFRA2 |
More about : GFRA2 |
| Long gene name: |
GDNF family receptor alpha 2 |
| Synonyms: |
RETL2 GDNFRB NTNRA TRNR2 |
| Locus: |
8p21, 3 |
| Discovery year: |
1997-10-21 |
| GenBank acession: |
AF002700 |
| Entrez gene record: |
2675 |
| Pubmed identfication: |
9177201 |
| RefSeq identity: |
NM_001495 |
| Havana BLAST/BLAT: |
OTTHUMG00000163897 |