| Long name: |
CARD11 Primary Polyclonal Antibody |
| Also known as: |
CARD11 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
CARD11 |
| Specificity: |
This is a highly specific antibody against CARD11 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CARD11 |
| Gene ID number: |
84433 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
The CARD domains of both proteins have been shown to specifically interact with BCL10, This protein has a domain structure similar to that of CARD14 protein, This protein is also a member of the CARD protein family, When expressed in cells, a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation, this protein activated NF-kappaB and induced the phosphorylation of BCL10, which is defined by carrying a characteristic caspase-associated recruitment domain (CARD), The protein encoded by this gene belongs to the membrane-associated guanylate kinase (MAGUK) family |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
BIMP 3, BIMP3, CAR11_HUMAN, CARD 11, CARD containing MAGUK protein 3, CARD-containing MAGUK protein 1, CARD11, CARD11 protein, CARMA1, Card maguk protein 1, Carma 1, Caspase recruitment domain containing protein 11, Caspase recruitment domain family member 11, Caspase recruitment domain-containing protein 11, MGC133069, Bcl10 interacting maguk protein 3 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
CARD11 |
| Short name: |
CARD11 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
member 11 (Antibody to), caspase recruitment domain family |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
CARD domain binding, CARD11 and IDBG-641196 and ENSBTAG00000014698 and 515377, CARD11 and IDBG-7145 and ENSG00000198286 and 84433, Card11 and IDBG-207118 and ENSMUSG00000036526 and 108723, Cell surfaces, member 11, this GO :0001772 and immunological synapse and cellular component this GO :0001819 and positive regulation of cytokine production and biological process this GO :0004385 and guanylate kinase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005622 and intracellular and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0007165 and signal transduction and biological process this GO :0030890 and positive regulation of B cell proliferation and biological process this GO :0031295 and T cell costimulation and biological process this GO :0038095 and Fc-epsilon receptor signaling pathway and biological process this GO :0042101 and T cell receptor complex and cellular component this GO :0042102 and positive regulation of T cell proliferation and biological process this GO :0042981 and regulation of apoptotic process and biological process this GO :0043123 and positive regulation of I-kappaB kinase/NF-kappaB signaling and biological process this GO :0045061 and thymic T cell selection and biological process this GO :0045086 and positive regulation of interleukin-2 biosynthetic process and biological process this GO :0045087 and innate immune response and biological process this GO :0045121 and membrane raft and cellular component this GO :0045577 and regulation of B cell differentiation and biological process this GO :0045580 and regulation of T cell differentiation and biological process this GO :0046939 and nucleotide phosphorylation and biological process this GO :0050700 and CARD domain binding and molecular function this GO :0050776 and regulation of immune response and biological process this GO :0050852 and T cell receptor signaling pathway and biological process this GO :0050870 and positive regulation of T cell activation and biological process this GO :0051092 and positive regulation of NF-kappaB transcription factor activity and biological process, this GO :0004385 : guanylate kinase activity, this GO :0004385 : guanylate kinase activity and also this GO :0005515 : protein binding and also this GO :0050700 : CARD domain binding, this GO :0005515 : protein binding, this GO :0050700 : CARD domain binding, caspase recruitment domain family |
| Identity: |
16393 |
| Gene: |
CARD11 |
More about : CARD11 |
| Long gene name: |
caspase recruitment domain family member 11 |
| Synonyms gene name: |
caspase recruitment domain family, member 11 |
| Synonyms: |
CARMA1 BIMP3 |
| Synonyms name: |
card-maguk protein 1 bcl10-interacting maguk protein 3 |
| Locus: |
7p22, 2 |
| Discovery year: |
2001-08-13 |
| GenBank acession: |
AF322641 |
| Entrez gene record: |
84433 |
| Pubmed identfication: |
11278692 11356195 |
| RefSeq identity: |
NM_032415 |
| Classification: |
Caspase recruitment domain containing Membrane associated guanylate kinases PDZ domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000023023 |
| Locus Specific Databases: |
LRG_729 |