| Long name: |
RND3 Primary Polyclonal Antibody |
| Also known as: |
RND3 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
RND3 |
| Specificity: |
This is a highly specific antibody against RND3 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human RND3 |
| Gene ID number: |
390 |
| Tested Applications: |
IF(IHC-P), IHC-P |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Cdc42-like, However, In their active form they interact with downstream proteins, Rac-like, Rho proteins have GTPase activity and bind GTP in their active form and GDP in their inactive form, Rnd and RhoBTB subfamilies, Rnd2 and RhoE(Rnd3), This family contains twenty different members divided into five groups, Thus, While Rho proteins are required for stress fibre formation in cultured fibroblasts, binds GTP but not GDP and has no GTPase activity, decrease in stress fibre), epithelial and endothelial cells, overexpression of Rnd3 or Rnd1 in the same cells may cause an opposite effect (i, the Rho-like, the Rnd subfamily of proteins containing the Rnd1, the Rnd3 protein may act as an antagonist for the Rho proteins either by directly binding to Rho or to other downstream proteins, The Rho family of proteins mediates cytoskeleton organization and cell motility responses, e |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
RND3_HUMAN, Rho family GTPase 3, Rho8, RhoE, memB, ARHE |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
RND3 |
| Short name: |
RND3 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
Rho family GTPase 3 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
ARHE and memB and Rho8 and RhoE, GTP binding, Plasma membranes, RND3 and IDBG-642057 and ENSBTAG00000039731 and 540224, RND3 and IDBG-72017 and ENSG00000115963 and 390, Rnd3 and IDBG-169060 and ENSMUSG00000017144 and 74194, this GO :0000139 and this GO lgi membrane and cellular component this GO :0003924 and GTPase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005525 and GTP binding and molecular function this GO :0005622 and intracellular and cellular component this GO :0006184 and GTP catabolic process and biological process this GO :0007155 and cell adhesion and biological process this GO :0007165 and signal transduction and biological process this GO :0007264 and small GTPase mediated signal transduction and biological process this GO :0015031 and protein transport and biological process this GO :0016020 and membrane and cellular component this GO :0030036 and actin cytoskeleton organization and biological process this GO :0070062 and extracellular vesicular exosome and cellular component, this GO :0003924 : GTPase activity, this GO :0003924 : GTPase activity and also this GO :0005515 : protein binding and also this GO :0005525 : GTP binding, this GO :0005515 : protein binding, this GO :0005525 : GTP binding, 783333, Rho family GTPase 3 |
| Identity: |
671 |
| Gene: |
RND3 |
More about : RND3 |
| Long gene name: |
Rho family GTPase 3 |
| Synonyms gene: |
ARHE |
| Synonyms gene name: |
member E , ras homolog gene family |
| Synonyms: |
RhoE Rho8 |
| Locus: |
2q23, 3 |
| Discovery year: |
1997-04-16 |
| Entrez gene record: |
390 |
| Pubmed identfication: |
8649376 |
| RefSeq identity: |
NM_005168 |
| Classification: |
Rho family GTPases |
| Havana BLAST/BLAT: |
OTTHUMG00000131859 |