| Long name: |
Recombinant Human Insulin receptor (INSR) |
| Alternative names: |
CD_antigen: CD220Cleaved into the following 2 chains:Insulin receptor subunit alpha, IR, Insulin receptor, Insulin receptor subunit beta, insulin receptor, insulin receptor, insulin receptor isoform Long preproprotein |
| Gene name: |
INSR |
| Other gene names: |
CD220, HHF5, INSR, IR, INSR |
| General description: |
All of our recombinant proteins are manufactured in strictly controlled facilities and by using a well established technology which guarantees full batch-to-bact consistency and experiment reproducibility, The protein can be with or without a His-Tag or other tag in accordance to customer's request, Insulin receptor (INSR) is a recombinant protein expressed in Mammalian Cell |
| Product category: |
Recombinant Proteins |
| Expression system: |
Mammalian Cell |
| Available also expressed in:: |
Baculovirus , Mammalian Cell, Yeast , E Coli |
| Purity: |
Greater than 90% (determined by SDS-PAGE) |
| Form: |
Lyophilized protein |
| Storage: |
Avoid cycles of freezing and thawing as they might denaturate the polypeptide chains, For extended periods of time it is recommended to keep the protein frozen at -40 or -80 degrees Celsius, This protein can be stored at -20 degrees Celsius |
| Applications: |
IFA, RIA, Western Blot, etc, This protein can be used as a positive control for applications such as ELISA |
| Properties: |
Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, Homo sapiens sapiens), Human proteins, humans , ssp |
| Description: |
2 or 3 and , However, In this sense, When such chemical-signals couple or bind to a receptor, a change in the electrical-activity of a cell, acetylcholine, am olfactory receptor is a protein-molecule that recognizes and responds to , an acetylcholine-receptor recognizes and responds to its endogenous-ligand, chemokinesor cytokines e, e, sometimes in pharmacology, such as enzymes, the term is also used to include other proteins that are drug-targets, they cause some form of cellular/tissue-response, transporters and ion-channels, The receptors are ligand binding factors of type 1, endogenous-chemical signals, g, g, protein-molecules , that receive chemical-signals from outside a cell |
| Gene target: |
Insulin receptor (INSR) |
| Short name: |
Insulin receptor (INSR) |
| Species: |
Humans, Human |
| Alternative name: |
sapiens Insulin receptor (insulin receptor), H |
| Alternative to gene target: |
BT, CD220 and HHF5, Cell surfaces, DNA-templated and biological process this GO :0006468 and protein phosphorylation and biological process this GO :0007169 and transmembrane receptor protein tyrosine kinase signaling pathway and biological process this GO :0007186 and G-protein coupled receptor signaling pathway and biological process this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0008286 and insulin receptor signaling pathway and biological process this GO :0008544 and epidermis development and biological process this GO :0009887 and organ morphogenesis and biological process this GO :0010008 and endosome membrane and cellular component this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0016772 and transferase activity, INSR and IDBG-22529 and ENSG00000171105 and 3643, Insr and IDBG-129570 and ENSMUSG00000005534 and 16337, this GO :0000187 and activation of MAPK activity and biological process this GO :0001934 and positive regulation of protein phosphorylation and biological process this GO :0003007 and heart morphogenesis and biological process this GO :0004672 and protein kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0004714 and transmembrane receptor protein tyrosine kinase activity and molecular function this GO :0004716 and receptor signaling protein tyrosine kinase activity and molecular function this GO :0005009 and insulin-activated receptor activity and molecular function this GO :0005159 and insulin-like growth factor receptor binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005525 and GTP binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0005899 and insulin receptor complex and cellular component this GO :0005901 and caveola and cellular component this GO :0005975 and carbohydrate metabolic process and biological process this GO :0006355 and regulation of transcription, this GO :0004672 : protein kinase activity, this GO :0004672 : protein kinase activity and also this GO :0004713 : protein tyrosine kinase activity and also this GO :0004714 : transmembrane receptor protein tyrosine kinase activity and also this GO :0004716 : receptor signaling protein tyrosine kinase activity and also this GO :0005009 : insulin-activated receptor activity and also this GO :0005159 : insulin-like growth factor receptor binding and also this GO :0005515 : protein binding and also this GO :0005524 : ATP binding and also this GO :0005525 : GTP binding and also this GO :0016772 : transferase activity, this GO :0004713 : protein tyrosine kinase activity, this GO :0004714 : transmembrane receptor protein tyrosine kinase activity, this GO :0004716 : receptor signaling protein tyrosine kinase activity, this GO :0005009 : insulin-activated receptor activity, this GO :0005159 : insulin-like growth factor receptor binding, this GO :0005515 : protein binding, this GO :0005524 : ATP binding, this GO :0005525 : GTP binding, this GO :0016772 : transferase activity, this GO :0031994 : insulin-like growth factor I binding, this GO :0031995 : insulin-like growth factor II binding, this GO :0043548 : phosphatidylinositol 3-kinase binding, this GO :0043559 : insulin binding, this GO :0043560 : insulin receptor substrate binding, this GO :0051425 : PTB domain binding, transferase activity, transferring phosphorus-containing groups, transferring phosphorus-containing groups and also this GO :0031994 : insulin-like growth factor I binding and also this GO :0031995 : insulin-like growth factor II binding and also this GO :0043548 : phosphatidylinositol 3-kinase binding and also this GO :0043559 : insulin binding and also this GO :0043560 : insulin receptor substrate binding and also this GO :0051425 : PTB domain binding, transferring phosphorus-containing groups and molecular function this GO :0018108 and peptidyl-tyrosine phosphorylation and biological process this GO :0019087 and transformation of host cell by virus and biological process this GO :0023014 and signal transduction by phosphorylation and biological process this GO :0030238 and male sex determination and biological process this GO :0030335 and positive regulation of cell migration and biological process this GO :0031017 and exocrine pancreas development and biological process this GO :0031994 and insulin-like growth factor I binding and molecular function this GO :0031995 and insulin-like growth factor II binding and molecular function this GO :0032147 and activation of protein kinase activity and biological process this GO :0032148 and activation of protein kinase B activity and biological process this GO :0032869 and cellular response to insulin stimulus and biological process this GO :0038083 and peptidyl-tyrosine autophosphorylation and biological process this GO :0042593 and glucose homeostasis and biological process this GO :0043235 and receptor complex and cellular component this GO :0043410 and positive regulation of MAPK cascade and biological process this GO :0043548 and phosphatidylinositol 3-kinase binding and molecular function this GO :0043559 and insulin binding and molecular function this GO :0043560 and insulin receptor substrate binding and molecular function this GO :0045429 and positive regulation of nitric oxide biosynthetic process and biological process this GO :0045725 and positive regulation of glycogen biosynthetic process and biological process this GO :0045740 and positive regulation of DNA replication and biological process this GO :0045821 and positive regulation of glycolytic process and biological process this GO :0045840 and positive regulation of mitosis and biological process this GO :0045995 and regulation of embryonic development and biological process this GO :0046326 and positive regulation of glucose import and biological process this GO :0046777 and protein autophosphorylation and biological process this GO :0048639 and positive regulation of developmental growth and biological process this GO :0051290 and protein heterotetramerization and biological process this GO :0051425 and PTB domain binding and molecular function this GO :0051897 and positive regulation of protein kinase B signaling and biological process this GO :0060267 and positive regulation of respiratory burst and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0071363 and cellular response to growth factor stimulus and biological process, 63550 and IDBG-643606 and ENSBTAG00000012687 and 408017, insulin receptor |
| Identity: |
6091 |
| Gene: |
INSR |
More about : INSR |
| Long gene name: |
insulin receptor |
| Synonyms: |
CD220 |
| Locus: |
19p13, 2 |
| Discovery year: |
1986-01-01 |
| GenBank acession: |
M10051 |
| Entrez gene record: |
3643 |
| Pubmed identfication: |
2983222 |
| Classification: |
CD molecules Fibronectin type III domain containing Receptor Tyrosine Kinases |
| Havana BLAST/BLAT: |
OTTHUMG00000181992 |