| Long name: |
FES Primary Polyclonal Antibody |
| Also known as: |
FES PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
FES |
| Specificity: |
This is a highly specific antibody against FES |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
140-190/822 |
| Subcellular location: |
Cytoplasm |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human FES |
| Gene ID number: |
2242 |
| Swiss Prot: |
P07332 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Acts down-stream of the activated FCER1 receptor and the mast/stem cell growth factor receptor KIT, PECAM1, Phosphorylates BCR and down-regulates BCR kinase activity, Phosphorylates HCLS1/HS1, Plays a role in FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells, Plays a role in cell scattering and cell migration in response to HGF-induced activation of EZR, Plays a role in the regulation of cell differentiation and promotes neurite outgrowth in response to NGF signaling, Plays a role in the regulation of mast cell degranulation, STAT3 and TRIM28, cell attachment and cell spreading, microtubule assembly, Tyrosine-protein kinase that acts downstream of cell surface receptors and plays a role in the regulation of the actin cytoskeleton |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
FES, Feline sarcoma/Fujinami avian sarcoma oncogene homolog, Proto-oncogene c-Fes, Proto-oncogene c-Fps, Tyrosine-protein kinase Fes/Fps, p93c-fes, FPS |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
FES |
| Short name: |
FES Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
FES (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
3657 |
| Gene: |
FES |
More about : FES |
| Long gene name: |
FES proto-oncogene, tyrosine kinase |
| Synonyms gene name: |
feline sarcoma (Snyder-Theilen) viral (v-fes)/Fujinami avian sarcoma (PRCII) viral (v-fps) oncogene homolog feline sarcoma oncogene |
| Synonyms: |
FPS |
| Synonyms name: |
Oncogene FES, feline sarcoma virus c-fes/fps protein |
| Locus: |
15q26, 1 |
| Discovery year: |
2001-06-22 |
| GenBank acession: |
X52192 |
| Entrez gene record: |
2242 |
| Pubmed identfication: |
1870997 |
| RefSeq identity: |
NM_002005 |
| Classification: |
SH2 domain containing F-BAR domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000044456 |