| Long name: |
P105 RB (Thr826) Primary Polyclonal Antibody |
| Also known as: |
P105 RB (Thr826) PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
P105 RB Thr826 |
| Specificity: |
This is a highly specific antibody against P105 RB Thr826 |
| Modification(s): |
Phosphorylation |
| Modification site(s): |
Thr826 |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic phosphopeptide derived from human Retinoblastoma associated protein around the phosphorylation site of Thr826 |
| Gene ID number: |
5925 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
ATF2, Aberrations in the Rb gene have been implicated in cancers of breast, Elf1 and cAbl, It forms a complex with SV40 large T antigen, PU1, Rb is phosphorylated on serine and threonine, Rb protein may act by regulating transcription and loss of its function leads to uncontrolled cell growth, This ability of Rb to alter transcription is regulated by phosphorylation catalyzed by the cyclin dependent protein kinases (cdks), UBF, adenovirus E1A, and human papilloma virus 16E, and leukemia, but not on tyrosine residues, colon, kidney, nasopharynx, prostate, Rb is a tumor suppressor gene which functions as a negative regulator of the cell cycle by interacting with transcription factors including E2F1 |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
Including osteosarcoma, OSRC, P105 RB, P105RB, PP105, PP110, RB 1, RB1, RB1 protein, RB_HUMAN, Retinoblastoma 1, Retinoblastoma 1 including osteosarcoma, Retinoblastoma associated protein, Retinoblastoma related osteosarcoma, Retinoblastoma susceptibility gene, pRb, RB1phospho T826 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
P105 RB (Thr826) |
| Short name: |
P105 RB (Thr826) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
P105 RB (Thr826) (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
7795 |
| Gene: |
NFKB2 |
More about : NFKB2 |
| Long gene name: |
nuclear factor kappa B subunit 2 |
| Synonyms gene name: |
nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) |
| Synonyms: |
LYT-10 p52 p105 NF-kB2 p49/p100 |
| Locus: |
10q24, 32 |
| Discovery year: |
1991-11-14 |
| GenBank acession: |
X61498 |
| Entrez gene record: |
4791 |
| Pubmed identfication: |
1876189 |
| Classification: |
Ankyrin repeat domain containing NF-kappa B complex subunits |
| Havana BLAST/BLAT: |
OTTHUMG00000018962 |