P105 RB (Ser795) Antibody, ALEXA FLUOR 488

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Catalog number: bs-5666R-A488
Price: 332 €
Supplier: Bioss Primary Conjugated Antibodies.
Product name: P105 RB (Ser795) Antibody, ALEXA FLUOR 488
Quantity: 100ul
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Long name: ALEXA FLUOR 488 Conjugated, P105 RB (Ser795) Polyclonal Antibody
Also known as: Anti-P105 RB Ser795 PAb ALEXA FLUOR 488
Category: Conjugated Primary Antibodies
Conjugated with: 488, ALEXA FLUOR®
Host Organism: Rabbit (Oryctolagus cuniculus)
Target Antigen: P105 RB Ser795
Specificity: This is a highly specific antibody against P105 RB Ser795
Modification: Phosphorylation
Modification Site: Ser795
Clonality: Polyclonal
Clone: Polyclonal antibody
Concentration: 1ug per 1ul
Source: KLH conjugated synthetic phosphopeptide derived from human P105 RB around the phosphorylation site of Ser795
Gene ID Number: 5925
Tested applications: IF(IHC-P)
Recommended dilutions: IF(IHC-P)(1:50-200)
Crossreactivity: Mouse, Rat, Human
Cross-reactive species details: not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen: ATF2, Aberrations in the Rb gene have been implicated in cancers of breast, Elf1 and cAbl, It forms a complex with SV40 large T antigen, PU1, Rb is phosphorylated on serine and threonine, Rb protein may act by regulating transcription and loss of its function leads to uncontrolled cell growth, This ability of Rb to alter transcription is regulated by phosphorylation catalyzed by the cyclin dependent protein kinases (cdks), UBF, adenovirus E1A, and human papilloma virus 16E, and leukemia, but not on tyrosine residues, colon, kidney, nasopharynx, prostate, Rb is a tumor suppressor gene which functions as a negative regulator of the cell cycle by interacting with transcription factors including E2F1
Purification: Purified by Protein A
Storage conditions: 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission: 499nm/519nm
Synonyms: LYT-10 p52 p105 NF-kB2 p49/p100
Properties: ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the P105 RB (Ser795) Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation: Alexa Fluor
Gene target: P105 RB (Ser795)
Short name: P105 RB (Ser795) Antibody
Technique: antibodies against human proteins, antibodies for, Antibody
Label: ALEXA FLUOR 488
Alternative name: ALEXA FLUOR 488, P105 RB (Ser795) (Antibody to)
Alternative technique: antibodies
Identity: 7795
Gene: NFKB2 | More about : NFKB2
Long gene name: nuclear factor kappa B subunit 2
Synonyms gene name: nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
Locus: 10q24, 32
Discovery year: 1991-11-14
GenBank acession: X61498
Entrez gene record: 4791
Pubmed identfication: 1876189
Classification: Ankyrin repeat domain containing NF-kappa B complex subunits
Havana BLAST/BLAT: OTTHUMG00000018962

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