| Long name: |
Cy5, 5 Conjugated, P105 RB(Ser612) Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Cy5, 5, 5, Cy5 |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
P105 RB Ser612 |
| Specificity: |
This is a highly specific antibody against P105 RB Ser612 |
| Modification: |
Phosphorylation |
| Modification site: |
Ser612 |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic phosphopeptide derived from human Retinoblastoma associated protein around the phosphorylation site of Ser612 |
| Gene ID number: |
5925 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
ATF2, Aberrations in the Rb gene have been implicated in cancers of breast, Elf1 and cAbl, It forms a complex with SV40 large T antigen, PU1, Rb is phosphorylated on serine and threonine, Rb protein may act by regulating transcription and loss of its function leads to uncontrolled cell growth, This ability of Rb to alter transcription is regulated by phosphorylation catalyzed by the cyclin dependent protein kinases (cdks), UBF, adenovirus E1A, and human papilloma virus 16E, and leukemia, but not on tyrosine residues, colon, kidney, nasopharynx, prostate, Rb is a tumor suppressor gene which functions as a negative regulator of the cell cycle by interacting with transcription factors including E2F1 |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
675nm/694nm |
| Synonyms: |
LYT-10 p52 p105 NF-kB2 p49/p100 |
| Properties: |
Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Conjugated: |
These antibodies are excite for emission at 678nm and detected at a 694 , nm wavelengths |
| Gene target: |
P105 RB(Ser612) Conjugated |
| Short name: |
Conjugated, P105 RB(Ser612) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
5, Cy5 |
| Alternative name: |
cyanine 5, 5 coupled, P105 RB(Ser612) (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
7795 |
| Gene: |
NFKB2 |
More about : NFKB2 |
| Long gene name: |
nuclear factor kappa B subunit 2 |
| Synonyms gene name: |
nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) |
| Locus: |
10q24, 32 |
| Discovery year: |
1991-11-14 |
| GenBank acession: |
X61498 |
| Entrez gene record: |
4791 |
| Pubmed identfication: |
1876189 |
| Classification: |
Ankyrin repeat domain containing NF-kappa B complex subunits |
| Havana BLAST/BLAT: |
OTTHUMG00000018962 |