| Long name: |
Tau protein(Ser214) Primary Polyclonal Antibody |
| Also known as: |
Tau protein(Ser214) PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
Tau protein Ser214 |
| Specificity: |
This is a highly specific antibody against Tau protein Ser214 |
| Modification(s): |
Phosphorylation |
| Modification site(s): |
Ser214 |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
190-230/441 |
| Subcellular location: |
Cytoplasm |
| Source: |
KLH conjugated synthetic phosphopeptide derived from human Tau protein isoform TauF around the phosphorylation site of Ser214 [TP(p-S)LP] |
| Gene ID number: |
4137 |
| Swiss Prot: |
P10636 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome, The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization, and might be involved in the establishment and maintenance of neuronal polarity, suggesting that tau functions as a linker protein between both, Promotes microtubule assembly and stability |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
DDPAC, FTDP-17, MAPT, MAPTL, MSTD, MTBT1, MTBT2, Microtubule-associated protein tau, Neurofibrillary tangle protein, PHF-tau, PPND, PPP1R13, Paired helical filament-tau, TAU |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
Tau protein(Ser214) |
| Short name: |
Tau protein(Ser214) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
Taurine protein(Ser214) (Antibody to) |
| Alternative technique: |
antibodies |