| Long name: |
ALEXA FLUOR 488 Conjugated, NMDAR2B (Tyr1336) Polyclonal Antibody |
| Also known as: |
Anti-NMDAR2B Tyr1336 PAb ALEXA FLUOR 488 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
488, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
NMDAR2B Tyr1336 |
| Specificity: |
This is a highly specific antibody against NMDAR2B Tyr1336 |
| Modification: |
Phosphorylation |
| Modification Site: |
Tyr1336 |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
1310-1360/1484 |
| Subcellular location: |
Cytoplasm |
| Source: |
KLH conjugated synthetic phosphopeptide derived from human NMDAR2B around the phosphorylation site of Tyr1336 |
| Gene ID Number: |
2904 |
| Swiss Prot: |
Q13224 |
| Tested applications: |
IF(IHC-P), FCM |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), FCM(1:20-100) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
In concert with DAPK1 at extrasynaptic sites, Its phosphorylation at Ser-1303 by DAPK1 enhances synaptic NMDA receptor channel activity inducing injurious Ca2+ influx through them, Mediated by glycine, acts as a central mediator for stroke damage, resulting in an irreversible neuronal death (By similarity), NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
499nm/519nm |
| Synonyms: |
GluN2B |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the NMDAR2B (Tyr1336) Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
NMDAR2B (Tyr1336) |
| Short name: |
NMDAR2B (Tyr1336) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 488 |
| Alternative name: |
ALEXA FLUOR 488, NMDAR2B (Tyr1336) (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
4586 |
| Gene: |
GRIN2B |
More about : GRIN2B |
| Long gene name: |
glutamate ionotropic receptor NMDA type subunit 2B |
| Synonyms gene: |
NMDAR2B |
| Synonyms gene name: |
N-methyl D-aspartate 2B , glutamate receptor, ionotropic |
| Locus: |
12p13, 1 |
| Discovery year: |
1992-09-18 |
| Entrez gene record: |
2904 |
| Pubmed identfication: |
1350383 |
| Classification: |
Glutamate ionotropic receptor NMDA type subunits |
| Havana BLAST/BLAT: |
OTTHUMG00000137373 |