| Long name: |
ALEXA FLUOR 594 Conjugated, EIF4G1 (Ser1238) Polyclonal Antibody |
| Also known as: |
Anti-E4G1 Ser1238 PAb ALEXA FLUOR 594 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
E4G1 Ser1238 |
| Specificity: |
This is a highly specific antibody against E4G1 Ser1238 |
| Modification: |
Phosphorylation |
| Modification Site: |
Ser1238 |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic phosphopeptide derived from human EIF4G1 around the phosphorylation site of Ser1238 |
| Gene ID Number: |
1981 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
A domain at its N-terminus can also interact with the poly(A)-binding protein, Alternative splicing results in multiple transcript variants, Human eIF4G contains three consecutive HEAT domains, The interactions of eIF4G1 with other factors are largely unknown, The recognition of the mRNA cap and the ATP-dependent unwinding of 5'-terminal secondary structure is catalyzed by factors in this complex, The subunit encoded by this gene is a large scaffolding protein that contains binding sites for other members of the EIF4F complex, This complex facilitates the recruitment of mRNA to the ribosome, Together with the cap-binding protein eIF4E, [provided by RefSeq], as well as long unstructured regions involved in multiple protein-protein interactions, eIF4G plays a critical role in protein expression and is at the center of a complex regulatory network, it recruits the small ribosomal subunit to the 5'-end of mRNA and promotes the assembly of a functional translation initiation complex which scans along the mRNA to the translation start codon, some of which are derived from alternative promoter usage, which is a rate-limiting step during the initiation phase of protein synthesis, which may mediate the circularization of mRNA during translation, The protein encoded by this gene is a component of the multi-subunit protein complex EIF4F, eIF4G1 (eukaryotic translation Initiation Factor 4 Gamma 1) is a component of the protein complex eIF-4 which is involved in the recognition of the mRNA cap ATP-dependent unwinding of the 5'-terminal secondary structure and recruitment of mRNA to the ribosome |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
p220 PARK18 |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
594, ALEXA FLUOR®, Alexa Fluor |
| Conjugated: |
Alexa conjugate 1 |
| Gene target: |
EIF4G1 (Ser1238) |
| Short name: |
EIF4G1 (Ser1238) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 594 |
| Alternative name: |
ALEXA FLUOR 594, EIF4G1 (Ser1238) (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
3296 |
| Gene: |
EIF4G1 |
More about : EIF4G1 |
| Long gene name: |
eukaryotic translation initiation factor 4 gamma 1 |
| Synonyms gene: |
EIF4G EIF4F |
| Synonyms gene name: |
1 , eukaryotic translation initiation factor 4 gamma |
| Locus: |
3q27, 1 |
| Discovery year: |
1993-06-17 |
| GenBank acession: |
D12686 |
| Entrez gene record: |
1981 |
| Pubmed identfication: |
1429670 9372926 21907011 |
| RefSeq identity: |
NM_182917 |
| Classification: |
Parkinson disease associated genes |
| Havana BLAST/BLAT: |
OTTHUMG00000156784 |