| Long name: |
ALEXA FLUOR 350 Conjugated, Desmin (Thr17) Polyclonal Antibody |
| Also known as: |
Anti-Desmin Thr17 PAb ALEXA FLUOR 350 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
350, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Desmin Thr17 |
| Specificity: |
This is a highly specific antibody against Desmin Thr17 |
| Modification: |
Phosphorylation |
| Modification Site: |
Thr17 |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic phosphopeptide derived from human DES around the phosphorylation site of Thr17 |
| Gene ID Number: |
1674 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
A desmin related myopathy can have a distal onset, Antidesmin are useful in identification of tumours of myogenic origin, CMD1I is an autosomal form of dilated cardiomyopathy characterized by ventricular dilatation and impaired systolic function, CSM is characterized by skeletal muscle weakness associated with cardiac conduction blocks, Defects in Desmin are also the cause of dilated cardiomyopathy type 1I (CMD1I), Defects in Desmin are the cause of desmin related cardio skeletal myopathy (CSM) also known as desmin related myopathy (DRM), In adult striated muscle they form a fibrous network connecting myofibrils to each other and to the plasma membrane from the periphery of the Z line structures, and by intracytoplasmic accumulation of desmin reactive deposits in cardiac and skeletal muscle cells, arrhythmias, it is then known as hereditary distal myopathy (HDM), restrictive heart failure, filaments found in muscle cells |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
343nm/442nm |
| Synonyms: |
CMD1I, CSM1, CSM2, DES, DESM_HUMAN, Desmin phospho Thr17, FLJ12025, FLJ39719, FLJ41013, FLJ41793, Intermediate filament protein, OTTHUMP00000064865, Desmin phospho Thr17 |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 350, Alexa Fluor |
| Gene: |
DSM1 and DSM2 play an important role in Desminopathy, Desmin regulated Myofibrilate Myopathy is a protein filament mutation of muscle proteins, Desmins or DES proteins detect by anti-desmin antibodies and DES ELISA kits |
More about : DSM1 and DSM2 play an important role in Desminopathy, Desmin regulated Myofibrilate Myopathy is a protein filament mutation of muscle proteins, Desmins or DES proteins detect by anti-desmin antibodies and DES ELISA kits |
| Gene target: |
Desmin (Thr17) |
| Short name: |
Desmin (Thr17) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 350 |
| Alternative name: |
ALEXA FLUOR 350, Desmin (Thr17) (Antibody to) |
| Alternative technique: |
antibodies |