| Long name: |
CHEK1 (Ser280) Primary Polyclonal Antibody |
| Also known as: |
CHEK1 (Ser280) PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
CHEK1 Ser280 |
| Specificity: |
This is a highly specific antibody against CHEK1 Ser280 |
| Modification(s): |
Phosphorylation |
| Modification site(s): |
Ser280 |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic phosphopeptide derived from mouse CHEK1 around the phosphorylation site of Ser280 |
| Gene ID number: |
1111 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
It is required for checkpoint mediated cell cycle arrest in response to DNA damage or the presence of unreplicated DNA, Oct 2011], Phosphorylation of CDC25A protein phosphatase by this protein is required for cells to delay cell cycle progression in response to double-strand DNA breaks, Several alternatively spliced transcript variants have been found for this gene, This protein acts to integrate signals from ATM and ATR, [provided by RefSeq, that also associate with chromatin in meiotic prophase I, two cell cycle proteins involved in DNA damage responses, The protein encoded by this gene belongs to the Ser/Thr protein kinase family |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
1, C85740, CHEK 1, CHEK-1, CHEK1, CHEK1 phospho Ser280, CHEK1 phospho Ser280, CHK1 checkpoint homolog S, CHK1_HUMAN, Cell cycle checkpoint kinase, Checkpoint, Checkpoint kinase 1, Checkpoint kinase 1 homolog S, Chk 1, Chk1, EC 2, S, STT3, Serine/threonine protein kinase Chk1, Serine/threonine-protein kinase CHK1, cerevisiae, homolog A S, homolog of, p-CHEK1 Ser280, pombe, pombe, pombe, rad27, subunit of the oligosaccharyltransferase complex, 1, 7, 11, Chk1 Ser280 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
CHEK1 (Ser280) |
| Short name: |
CHEK1 (Ser280) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
CHEK1 (Ser280) (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
1925 |
| Gene: |
CHEK1 |
More about : CHEK1 |
| Long gene name: |
checkpoint kinase 1 |
| Synonyms gene name: |
CHK1 (checkpoint, S, pombe) , pombe) homolog CHK1 checkpoint homolog (S |
| Synonyms: |
CHK1 |
| Locus: |
11q24, 2 |
| Discovery year: |
1998-04-21 |
| GenBank acession: |
AF016582 BC017575 |
| Entrez gene record: |
1111 |
| Pubmed identfication: |
9278511 9382850 |
| RefSeq identity: |
NM_001274 |
| Havana BLAST/BLAT: |
OTTHUMG00000165853 |