| Long name: |
BACE1 (Ser498) Primary Polyclonal Antibody |
| Also known as: |
BACE1 (Ser498) PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
BACE1 Ser498 |
| Specificity: |
This is a highly specific antibody against BACE1 Ser498 |
| Modification(s): |
Phosphorylation |
| Modification site(s): |
Ser498 |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic phosphopeptide derived from human BACE1 around the phosphorylation site of Ser498 |
| Gene ID number: |
23621 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein(APP) by two proteases, Multiple transcript variants encoding different isoforms have been described for this gene, The encoded protein, [provided by RefSeq], a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease that is found mainly in the Golgi, one of which is the protein encoded by this gene, Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
APP beta secretase, ASP2, Asp 2, Aspartyl protease 2, BACE, BACE 1, BACE1 S498, BACE1_HUMAN, Beta secretase, Beta secretase 1, Beta site APP cleaving enzyme, Beta site APP cleaving enzyme 1, Beta site amyloid beta A4 precursor protein cleaving enzyme, Beta site amyloid precursor protein cleaving enzyme, Beta site amyloid precursor protein cleaving enzyme 1, Beta-secretase 1, Beta-site APP cleaving enzyme 1, Beta-site amyloid precursor protein cleaving enzyme 1, FLJ90568, HSPC104, KIAA1149, Memapsin 2, Memapsin-2, Memapsin2, Membrane associated aspartic protease 2, Membrane-associated aspartic protease 2, Transmembrane aspartic proteinase Asp2, p-BACE1 Se498, p-BACE1 Ser498, BACE1 Ser498 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
BACE1 (Ser498) |
| Short name: |
BACE1 (Ser498) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
BACE1 (Ser498) (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
933 |
| Gene: |
BACE1 |
More about : BACE1 |
| Long gene name: |
beta-secretase 1 |
| Synonyms gene: |
BACE |
| Synonyms gene name: |
beta-site APP-cleaving enzyme beta-site APP-cleaving enzyme 1 |
| Locus: |
11q23, 3 |
| Discovery year: |
1999-10-29 |
| GenBank acession: |
AF190725 |
| Entrez gene record: |
23621 |
| Pubmed identfication: |
10531052 |
| Havana BLAST/BLAT: |
OTTHUMG00000160636 |