| Long name: |
Primary Polyclonal Antibody, PKC &epsilon |
| Also known as: |
PAb, PKC &epsilon |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
PKC &epsilon |
| Specificity: |
This is a highly specific antibody against PKC &epsilon |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Source: |
Synthetic peptide |
| Gene ID number: |
5581 |
| Swiss Prot: |
Q02156 |
| Tested Applications: |
WB |
| Recommended dilutions: |
WB (1:2000) |
| Cross reactivity: |
Rat, Mouse |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
&beta, &delta, &epsilon, &eta, All family members require phosphatidylserine, Based on their structures and sensitivities to Ca2+ and diacylglycerol (DAG), Constitutive activation of PKC&epsilon, PKC epsilon (PKC&epsilon, PKC&epsilon, PKC&gamma, PKC&iota, PKCs share a structural backbone, Some PKCs (PKC&alpha, The family is composed of several genes that express structurally related phospholipid-dependent kinases with distinct means of regulation and tissue distribution, a component of the phospholipid bilayer, and &gamma, and &lambda, and &theta, and &zeta, and PKC&theta, and atypical PKCs (&zeta, and cell death, but other isoforms are expressed in a tissue-specific manner, differentiation, for example, for their activation, in a small cell lung cancer (SCLC) cell line and the overexpression of PKC&epsilon, in colonic epithelial cells have been reported, is largely confined to brain and neuronal tissue, is mainly expressed in skeletal muscle, is mainly expressed in testis and insulin secreting cells, is the only PKC isozyme that has been shown to behave as an oncoprotein, mainly consisting of a regulatory domain at the N-terminus and a catalytic domain at the C-terminus, novel PKCs (&delta, proliferation, they have been classified into conventional PKCs (&alpha, ), ), ), ) are widely expressed in all tissues, ) is a calcium-independent and phorbolester/diacylglycerol-sensitive serine/threonine kinase, /&iota, Protein kinase C (PKC) is a family of serine-threonine kinases that regulate a broad spectrum of cellular functions such as cell migration and polarity |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
PRKCE, Protein kinase C epsilon type, nPKC-epsilon, PKCE |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
PKC &epsilon |
| Short name: |
Antibody, PKC &epsilon |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
(Antibody to), PKC &epsilon |
| Alternative technique: |
antibodies |
| Identity: |
30500 |
| Gene: |
PRRT2 |
More about : PRRT2 |
| Long gene name: |
proline rich transmembrane protein 2 |
| Synonyms gene: |
ICCA DYT10 |
| Synonyms gene name: |
infantile convulsions and paroxysmal choreoathetosis dystonia 10 proline-rich transmembrane protein 2 |
| Synonyms: |
FLJ25513 DKFZp547J199 IFITMD1 FICCA DSPB3 PKC EKD1 |
| Synonyms name: |
interferon induced transmembrane protein domain containing 1 |
| Locus: |
16p11, 2 |
| Discovery year: |
2005-11-25 |
| GenBank acession: |
BC011405 |
| Entrez gene record: |
112476 |
| Pubmed identfication: |
22101681 22243967 |
| RefSeq identity: |
NM_145239 |
| Classification: |
Proline rich transmembrane proteins |
| Havana BLAST/BLAT: |
OTTHUMG00000177142 |