| Long name: |
ALEXA FLUOR 555 Conjugated, APOE Polyclonal Antibody |
| Also known as: |
Anti-APOE PAb ALEXA FLUOR 555 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
555, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
APOE |
| Specificity: |
This is a highly specific antibody against APOE |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
120-170/310 |
| Subcellular location: |
Secreted |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human APOE3 |
| Gene ID Number: |
348 |
| Swiss Prot: |
P02649 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
It can serve as a ligand for the LDL (apo B/E) receptor and for the specific apo-E receptor (chylomicron remnant) of hepatic tissues, and catabolism of lipoprotein particles, internalization, Mediates the binding |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
553nm/568nm |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, Very high photo stable ALEXA conjugate, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 555, Alexa Fluor |
| Gene target: |
APOE |
| Short name: |
APOE Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 555 |
| Alternative name: |
ALEXA FLUOR 555, apolipoprotein E (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
AD2 and LDLCQ5 and LPG, APOE and IDBG-56807 and ENSG00000130203 and 348, APOE and IDBG-639311 and ENSBTAG00000010123 and 281004, Apoe and IDBG-152108 and ENSMUSG00000002985 and 11816, cholinergic and biological process this GO :0007568 and aging and biological process this GO :0007603 and phototransduction, lipoprotein particle binding, nuclei, this GO :0000302 and response to reactive oxygen species and biological process this GO :0001523 and retinoid metabolic process and biological process this GO :0001540 and beta-amyloid binding and molecular function this GO :0001937 and negative regulation of endothelial cell proliferation and biological process this GO :0002021 and response to dietary excess and biological process this GO :0005102 and receptor binding and molecular function this GO :0005319 and lipid transporter activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005543 and phospholipid binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005615 and extracellular space and cellular component this GO :0005634 and nucleus and cellular component this GO :0005635 and nuclear envelope and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005764 and lysosome and cellular component this GO :0005768 and endosome and cellular component this GO :0005769 and early endosome and cellular component this GO :0005770 and late endosome and cellular component this GO :0005783 and endoplasmic reticulum and cellular component this GO :0005794 and this GO lgi apparatus and cellular component this GO :0005874 and microtubule and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006629 and lipid metabolic process and biological process this GO :0006641 and triglyceride metabolic process and biological process this GO :0006707 and cholesterol catabolic process and biological process this GO :0006869 and lipid transport and biological process this GO :0006874 and cellular calcium ion homeostasis and biological process this GO :0006898 and receptor-mediated endocytosis and biological process this GO :0006979 and response to oxidative stress and biological process this GO :0007010 and cytoskeleton organization and biological process this GO :0007186 and G-protein coupled receptor signaling pathway and biological process this GO :0007263 and nitric oxide mediated signal transduction and biological process this GO :0007271 and synaptic transmission, this GO :0001540 : beta-amyloid binding, this GO :0001540 : beta-amyloid binding and also this GO :0005102 : receptor binding and also this GO :0005319 : lipid transporter activity and also this GO :0005515 : protein binding and also this GO :0005543 : phospholipid binding and also this GO :0008201 : heparin binding and also this GO :0008289 : lipid binding and also this GO :0016209 : antioxidant activity and also this GO :0017127 : cholesterol transporter activity and also this GO :0042802 : identical protein binding and also this GO :0042803 : protein homodimerization activity and also this GO :0046848 : hydroxyapatite binding and also this GO :0046911 : metal chelating activity and also this GO :0048156 : tau protein binding and also this GO :0050750 : low-density lipoprotein particle receptor binding and also this GO :0060228 : phosphatidylcholine-sterol O-acyltransferase activator activity and also this GO :0070326 : very-low-density lipoprotein particle receptor binding and also this GO :0071813 : lipoprotein particle binding, this GO :0005102 : receptor binding, this GO :0005319 : lipid transporter activity, this GO :0005515 : protein binding, this GO :0005543 : phospholipid binding, this GO :0008201 : heparin binding, this GO :0008289 : lipid binding, this GO :0016209 : antioxidant activity, this GO :0017127 : cholesterol transporter activity, this GO :0042802 : identical protein binding, this GO :0042803 : protein homodimerization activity, this GO :0046848 : hydroxyapatite binding, this GO :0046911 : metal chelating activity, this GO :0048156 : tau protein binding, this GO :0050750 : low-density lipoprotein particle receptor binding, this GO :0060228 : phosphatidylcholine-sterol O-acyltransferase activator activity, this GO :0070326 : very-low-density lipoprotein particle receptor binding, this GO :0071813 : lipoprotein particle binding, visible light and biological process this GO :0008201 and heparin binding and molecular function this GO :0008203 and cholesterol metabolic process and biological process this GO :0008219 and cell death and biological process this GO :0008289 and lipid binding and molecular function this GO :0009986 and cell surface and cellular component this GO :0010468 and regulation of gene expression and biological process this GO :0010544 and negative regulation of platelet activation and biological process this GO :0010873 and positive regulation of cholesterol esterification and biological process this GO :0010875 and positive regulation of cholesterol efflux and biological process this GO :0014012 and peripheral nervous system axon regeneration and biological process this GO :0015909 and long-chain fatty acid transport and biological process this GO :0016020 and membrane and cellular component this GO :0016209 and antioxidant activity and molecular function this GO :0017038 and protein import and biological process this GO :0017127 and cholesterol transporter activity and molecular function this GO :0019934 and cGMP-mediated signaling and biological process this GO :0030195 and negative regulation of blood coagulation and biological process this GO :0030425 and dendrite and cellular component this GO :0030516 and regulation of axon extension and biological process this GO :0030828 and positive regulation of cGMP biosynthetic process and biological process this GO :0031232 and extrinsic component of external side of plasma membrane and cellular component this GO :0032489 and regulation of Cdc42 protein signal transduction and biological process this GO :0032526 and response to retinoic acid and biological process this GO :0032805 and positive regulation of low-density lipoprotein particle receptor catabolic process and biological process this GO :0032868 and response to insulin and biological process this GO :0033344 and cholesterol efflux and biological process this GO :0033700 and phospholipid efflux and biological process this GO :0034361 and very-low-density lipoprotein particle and cellular component this GO :0034362 and low-density lipoprotein particle and cellular component this GO :0034363 and intermediate-density lipoprotein particle and cellular component this GO :0034364 and high-density lipoprotein particle and cellular component this GO :0034365 and discoidal high-density lipoprotein particle and cellular component this GO :0034372 and very-low-density lipoprotein particle remodeling and biological process this GO :0034374 and low-density lipoprotein particle remodeling and biological process this GO :0034375 and high-density lipoprotein particle remodeling and biological process this GO :0034380 and high-density lipoprotein particle assembly and biological process this GO :0034382 and chylomicron remnant clearance and biological process this GO :0034384 and high-density lipoprotein particle clearance and biological process this GO :0034447 and very-low-density lipoprotein particle clearance and biological process this GO :0042157 and lipoprotein metabolic process and biological process this GO :0042158 and lipoprotein biosynthetic process and biological process this GO :0042159 and lipoprotein catabolic process and biological process this GO :0042311 and vasodilation and biological process this GO :0042627 and chylomicron and cellular component this GO :0042632 and cholesterol homeostasis and biological process this GO :0042802 and identical protein binding and molecular function this GO :0042803 and protein homodimerization activity and molecular function this GO :0043025 and neuronal cell body and cellular component this GO :0043407 and negative regulation of MAP kinase activity and biological process this GO :0043524 and negative regulation of neuron apoptotic process and biological process this GO :0043537 and negative regulation of blood vessel endothelial cell migration and biological process this GO :0043691 and reverse cholesterol transport and biological process this GO :0044281 and small molecule metabolic process and biological process this GO :0045471 and response to ethanol and biological process this GO :0045541 and negative regulation of cholesterol biosynthetic process and biological process this GO :0045773 and positive regulation of axon extension and biological process this GO :0046848 and hydroxyapatite binding and molecular function this GO :0046889 and positive regulation of lipid biosynthetic process and biological process this GO :0046907 and intracellular transport and biological process this GO :0046911 and metal chelating activity and molecular function this GO :0048156 and tau protein binding and molecular function this GO :0048168 and regulation of neuronal synaptic plasticity and biological process this GO :0048709 and oli this GO dendrocyte differentiation and biological process this GO :0048844 and artery morphogenesis and biological process this GO :0050728 and negative regulation of inflammatory response and biological process this GO :0050750 and low-density lipoprotein particle receptor binding and molecular function this GO :0051000 and positive regulation of nitric-oxide synthase activity and biological process this GO :0051044 and positive regulation of membrane protein ectodomain proteolysis and biological process this GO :0051055 and negative regulation of lipid biosynthetic process and biological process this GO :0051651 and maintenance of location in cell and biological process this GO :0055088 and lipid homeostasis and biological process this GO :0055089 and fatty acid homeostasis and biological process this GO :0060228 and phosphatidylcholine-sterol O-acyltransferase activator activity and molecular function this GO :0060999 and positive regulation of dendritic spine development and biological process this GO :0061000 and negative regulation of dendritic spine development and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0070326 and very-low-density lipoprotein particle receptor binding and molecular function this GO :0071347 and cellular response to interleukin-1 and biological process this GO :0071363 and cellular response to growth factor stimulus and biological process this GO :0071397 and cellular response to cholesterol and biological process this GO :0071682 and endocytic vesicle lumen and cellular component this GO :0071813 and lipoprotein particle binding and molecular function this GO :0072358 and cardiovascular system development and biological process this GO :0072562 and blood microparticle and cellular component this GO :0090370 and negative regulation of cholesterol efflux and biological process this GO :0097113 and alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor clustering and biological process this GO :0097114 and N-methyl-D-aspartate receptor clustering and biological process this GO :1900221 and regulation of beta-amyloid clearance and biological process this GO :1901214 and regulation of neuron death and biological process this GO :1901215 and negative regulation of neuron death and biological process this GO :1901216 and positive regulation of neuron death and biological process this GO :1901627 and negative regulation of postsynaptic membrane organization and biological process this GO :1901628 and positive regulation of postsynaptic membrane organization and biological process this GO :1901630 and negative regulation of presynaptic membrane organization and biological process this GO :1901631 and positive regulation of presynaptic membrane organization and biological process this GO :1902004 and positive regulation of beta-amyloid formation and biological process this GO :1902430 and negative regulation of beta-amyloid formation and biological process this GO :1902947 and regulation of tau-protein kinase activity and biological process this GO :1902951 and negative regulation of dendritic spine maintenance and biological process this GO :1902952 and positive regulation of dendritic spine maintenance and biological process this GO :1902995 and positive regulation of phospholipid efflux and biological process this GO :1902998 and positive regulation of neurofibrillary tangle assembly and biological process this GO :1902999 and negative regulation of phospholipid efflux and biological process this GO :1903001 and negative regulation of lipid transport across blood brain barrier and biological process this GO :1903002 and positive regulation of lipid transport across blood brain barrier and biological process, apolipoprotein E |
| Identity: |
613 |
| Gene: |
APOE |
More about : APOE |
| Long gene name: |
apolipoprotein E |
| Synonyms gene: |
AD2 |
| Synonyms gene name: |
Alzheimer disease 2 (APOE*E4-associated, late onset) |
| Locus: |
19q13, 32 |
| Discovery year: |
2001-06-22 |
| GenBank acession: |
K00396 |
| Entrez gene record: |
348 |
| Pubmed identfication: |
10662539 |
| RefSeq identity: |
NM_000041 |
| Classification: |
Apolipoproteins |
| Havana BLAST/BLAT: |
OTTHUMG00000128901 |
| Locus Specific Databases: |
ALSOD, the Amyotrophic Lateral Sclerosis Online Genetic Database |