| Long name: |
DNAJB6 Primary Polyclonal Antibody |
| Also known as: |
DNAJB6 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
DNAJB6 |
| Specificity: |
This is a highly specific antibody against DNAJB6 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human HSJ2/DNAJB6 |
| Gene ID number: |
10049 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Acts as an endogenous molecular chaperone for neuronal proteins including huntingtin, Also reduces cellular toxicity and caspase-3 activity, Has a stimulatory effect on the ATPase activity of HSP70 in a dose-dependent and time-dependent manner and hence acts as a co-chaperone of HSP70, Reduces huntingtin aggregation associated with HD, Plays an indispensable role in the organization of KRT8/KRT18 filaments |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
DNAJ B6, DNAJB6, DNJB6_HUMAN, DnaJ, DnaJ homolog subfamily B member 6, HHDJ1, HSJ-2, HSJ2, Heat shock protein J2, MRJ, MSJ-1, MSJ1, DJ4 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
DNAJB6 |
| Short name: |
DNAJB6 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
member 6 (Antibody to), subfamily B, DnaJ (Hsp40) homolog |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
DJ4 and DnaJ and HHDJ1 and HSJ-2 and HSJ2 and LGMD1D and LGMD1E and MRJ and MSJ-1, DNA-templated and biological process this GO :0048471 and perinuclear region of cytoplasm and cellular component this GO :0051082 and unfolded protein binding and molecular function this GO :0051087 and chaperone binding and molecular function this GO :0060710 and chorio-allantoic fusion and biological process this GO :0060715 and syncytiotrophoblast cell differentiation involved in labyrinthine layer development and biological process this GO :0060717 and chorion development and biological process this GO :0090084 and negative regulation of inclusion body assembly and biological process, DNAJB6 and IDBG-50846 and ENSG00000105993 and 10049, Dnajb3 and IDBG-394183 and ENSMUSG00000081984 and 15504, LOC528549 and IDBG-648942 and ENSBTAG00000018756 and 528549, chaperone binding, member 6, nuclei, subfamily B, this GO :0001671 and ATPase activator activity and molecular function this GO :0003677 and DNA binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0006457 and protein folding and biological process this GO :0016020 and membrane and cellular component this GO :0030018 and Z disc and cellular component this GO :0030036 and actin cytoskeleton organization and biological process this GO :0030198 and extracellular matrix organization and biological process this GO :0031072 and heat shock protein binding and molecular function this GO :0032781 and positive regulation of ATPase activity and biological process this GO :0034504 and protein localization to nucleus and biological process this GO :0043154 and negative regulation of cysteine-type endopeptidase activity involved in apoptotic process and biological process this GO :0045109 and intermediate filament organization and biological process this GO :0045892 and negative regulation of transcription, this GO :0001671 : ATPase activator activity, this GO :0001671 : ATPase activator activity and also this GO :0003677 : DNA binding and also this GO :0005515 : protein binding and also this GO :0031072 : heat shock protein binding and also this GO :0051082 : unfolded protein binding and also this GO :0051087 : chaperone binding, this GO :0003677 : DNA binding, this GO :0005515 : protein binding, this GO :0031072 : heat shock protein binding, this GO :0051082 : unfolded protein binding, this GO :0051087 : chaperone binding, 102724007, DnaJ (Hsp40) homolog |
| Identity: |
14888 |
| Gene: |
DNAJB6 |
More about : DNAJB6 |
| Long gene name: |
DnaJ heat shock protein family (Hsp40) member B6 |
| Synonyms gene: |
LGMD1D |
| Synonyms gene name: |
limb girdle muscular dystrophy 1D (autosomal dominant) DnaJ (Hsp40) homolog, member 6 , subfamily B |
| Synonyms: |
MRJ |
| Locus: |
7q36, 3 |
| Discovery year: |
2001-03-09 |
| GenBank acession: |
AB014888 |
| Entrez gene record: |
10049 |
| Pubmed identfication: |
10319584 9915854 22366786 |
| Classification: |
DNAJ (HSP40) heat shock proteins |
| Havana BLAST/BLAT: |
OTTHUMG00000157242 |