| Long name: |
Cy5, 5 Conjugated, TGF Beta 1+2+3 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Cy5, 5, 5, Cy5 |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
TGF Beta 1+2+3 |
| Specificity: |
This antibody will preferentially react with TGFB1, but will also detect TGFB2 (93%) and TGFB3 (86%) based upon sequence similarity, This is a highly specific antibody against TGF Beta 1+2+3 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
280-330/390 |
| Subcellular location: |
Secreted, Extracellular |
| Source: |
KLH conjugated synthetic peptide derived from human TGF Beta 1 |
| Gene ID number: |
7040 |
| Swiss Prot: |
P01137 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
At high concentrations, At low concentrations in concert with IL-6 and IL-21, Can promote either T-helper 17 cells (Th17) or regulatory T-cells (Treg) lineage differentiation in a concentration-dependent manner, It plays an important role in bone remodeling as it is a potent stimulator of osteoblastic bone formation, It positively and negatively regulates many other growth factors, Many cells synthesize TGFB1 and have specific receptors for it, causing chemotaxis, differentiation and other functions in many cell types, favoring Treg cell development, favoring differentiation to Th17 cells, leads to FOXP3-mediated suppression of RORC and down-regulation of IL-17 expression, leads to expression of the IL-17 and IL-23 receptors, proliferation and differentiation in committed osteoblasts, Multifunctional protein that controls proliferation |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
675nm/694nm |
| Synonyms: |
DPD1, LAP, TGF-beta-1, TGFB, TGFB1, TGFbeta, Transforming growth factor beta-1, CED |
| Properties: |
Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Conjugated: |
These antibodies are excite for emission at 678nm and detected at a 694 , nm wavelengths |
| Gene target: |
TGF Beta 1+2+3 Conjugated |
| Short name: |
Conjugated, TGF Beta 1+2+3 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
5, Cy5 |
| Alternative name: |
cyanine 5, 5 coupled, TGF b 1+2+3 (Antibody to) |
| Alternative technique: |
antibodies |