| Long name: |
ALEXA FLUOR 488 Conjugated, XPB Polyclonal Antibody |
| Also known as: |
Anti-XPB PAb ALEXA FLUOR 488 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
488, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
XPB |
| Specificity: |
This is a highly specific antibody against XPB |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
625-675/782 |
| Subcellular location: |
Nucleus |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human XPB/ERCC3 |
| Gene ID Number: |
2071 |
| Swiss Prot: |
P19447 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Acts by opening DNA either around the RNA transcription start site or the DNA damage, component of the core-TFIIH basal transcription factor, in RNA transcription by RNA polymerase II, involved in nucleotide excision repair (NER) of DNA and, when complexed to CAK, ATP-dependent 3'-5' DNA helicase |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
499nm/519nm |
| Synonyms: |
XPB BTF2 RAD25 TFIIH GTF2H |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the XPB Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
XPB |
| Short name: |
XPB Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 488 |
| Alternative name: |
ALEXA FLUOR 488, XPB (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
3435 |
| Gene: |
ERCC3 |
More about : ERCC3 |
| Long gene name: |
ERCC excision repair 3, TFIIH core complex helicase subunit |
| Synonyms gene name: |
complementation group 3 excision repair cross-complementation group 3 , excision repair cross-complementing rodent repair deficiency |
| Synonyms name: |
xeroderma pigmentosum group B complementing |
| Locus: |
2q14, 3 |
| Discovery year: |
2001-06-22 |
| GenBank acession: |
M31899 |
| Entrez gene record: |
2071 |
| Pubmed identfication: |
8202161 |
| RefSeq identity: |
NM_000122 |
| Classification: |
Xeroderma pigmentosum complementation groups General transcription factors ERCC excision repair associated DNA helicases |
| Havana BLAST/BLAT: |
OTTHUMG00000131530 |
| Locus Specific Databases: |
LRG_462 |