| Long name: |
ALEXA FLUOR 488 Conjugated, phospholamban Polyclonal Antibody |
| Also known as: |
Anti-phospholamban PAb ALEXA FLUOR 488 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
488, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
phospholamban |
| Specificity: |
This is a highly specific antibody against phospholamban |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human phospholamban |
| Gene ID Number: |
5350 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Believed to assemble into a pentamer, Non-phosphorylated PLB associates with SERCA2a, PKA, PKG, PLB activation occurs when key Serine/Threonine residues in PLB (Ser-10, PLB regulates cardiac contractility and Ca2+ affinity for cardiac SER Ca2+ ATPase (SERCA2a), Phospholamban (PLB), Phosphorylation of PLB causes dissociation from SERCA2a and a subsequent increase in the rate of Ca2+ reuptake into the SER, Ser-16, Thr-17) are phosphorylated by numerous effectors, and CaM kinase, and inhibits Ca2+ reuptake into the SER, is a small, plasma membrane-associated protein found in the SER of cardiac, smooth and slow-twitch muscle, which accelerates ventricular relaxation, which include PKC, The Sarco(endo)plasmic-reticulum (SER) regulatory protein |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
499nm/519nm |
| Synonyms: |
CMD1P |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the phospholamban Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
phospholamban |
| Short name: |
phospholamban Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 488 |
| Alternative name: |
ALEXA FLUOR 488, phospholamban (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
9080 |
| Gene: |
PLN |
More about : PLN |
| Long gene name: |
phospholamban |
| Synonyms gene: |
PLB |
| Locus: |
6q22, 31 |
| Discovery year: |
1991-08-22 |
| Entrez gene record: |
5350 |
| Pubmed identfication: |
1828805 |
| RefSeq identity: |
NM_002667 |
| Havana BLAST/BLAT: |
OTTHUMG00000015462 |
| Locus Specific Databases: |
LRG_390 |