| Long name: |
Cy5 Conjugated, CBL2 (Tyr700) Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
5, Cy5 |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
CBL2 Tyr700 |
| Specificity: |
This is a highly specific antibody against CBL2 Tyr700 |
| Modification: |
Phosphorylation |
| Modification site: |
Tyr700 |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic phosphopeptide derived from human C CBL around the phosphorylation site of Tyr700 |
| Gene ID number: |
867 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
As such it functions as a negative regulator of many signal transduction pathways, Mar 2012], Mutations in this gene are also the cause of Noonan syndrome-like disorder, The encoded protein is one of the enzymes required for targeting substrates for degradation by the proteasome, This gene has been found to be mutated or translocated in many cancers including acute myeloid leukaemia, This protein also contains an N-terminal phosphotyrosine binding domain that allows it to interact with numerous tyrosine-phosphorylated substrates and target them for proteasome degradation, This protein mediates the transfer of ubiquitin from ubiquitin conjugating enzymes (E2) to specific substrates, [provided by RefSeq, This gene is a proto-oncogene that encodes a RING finger E3 ubiquitin ligase |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
625, 650nm/670nm |
| Synonyms: |
RNF55 c-Cbl |
| Properties: |
Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
CBL2 (Tyr700) Conjugated |
| Short name: |
Conjugated, CBL2 (Tyr700) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Cy5 |
| Alternative name: |
cyanine 5 coupled, CBL2 (Tyr700) (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
1541 |
| Gene: |
CBL |
More about : CBL |
| Long gene name: |
Cbl proto-oncogene |
| Synonyms gene: |
CBL2 |
| Synonyms gene name: |
Cas-Br-M (murine) ecotropic retroviral transforming sequence Cbl proto-oncogene, E3 ubiquitin protein ligase |
| Synonyms name: |
oncogene CBL2 |
| Locus: |
11q23, 3 |
| Discovery year: |
1989-06-30 |
| GenBank acession: |
X57110 |
| Entrez gene record: |
867 |
| Pubmed identfication: |
2013228 |
| RefSeq identity: |
NM_005188 |
| Classification: |
Ring finger proteins |
| Havana BLAST/BLAT: |
OTTHUMG00000166170 |
| Locus Specific Databases: |
LRG_608 |