| Long name: |
ALEXA FLUOR 555 Conjugated, CBL2 (Tyr700) Polyclonal Antibody |
| Also known as: |
Anti-CBL2 Tyr700 PAb ALEXA FLUOR 555 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
555, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
CBL2 Tyr700 |
| Specificity: |
This is a highly specific antibody against CBL2 Tyr700 |
| Modification: |
Phosphorylation |
| Modification Site: |
Tyr700 |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic phosphopeptide derived from human C CBL around the phosphorylation site of Tyr700 |
| Gene ID Number: |
867 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
As such it functions as a negative regulator of many signal transduction pathways, Mar 2012], Mutations in this gene are also the cause of Noonan syndrome-like disorder, The encoded protein is one of the enzymes required for targeting substrates for degradation by the proteasome, This gene has been found to be mutated or translocated in many cancers including acute myeloid leukaemia, This protein also contains an N-terminal phosphotyrosine binding domain that allows it to interact with numerous tyrosine-phosphorylated substrates and target them for proteasome degradation, This protein mediates the transfer of ubiquitin from ubiquitin conjugating enzymes (E2) to specific substrates, [provided by RefSeq, This gene is a proto-oncogene that encodes a RING finger E3 ubiquitin ligase |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
553nm/568nm |
| Synonyms: |
RNF55 c-Cbl |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, Very high photo stable ALEXA conjugate, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 555, Alexa Fluor |
| Gene target: |
CBL2 (Tyr700) |
| Short name: |
CBL2 (Tyr700) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 555 |
| Alternative name: |
ALEXA FLUOR 555, CBL2 (Tyr700) (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
1541 |
| Gene: |
CBL |
More about : CBL |
| Long gene name: |
Cbl proto-oncogene |
| Synonyms gene: |
CBL2 |
| Synonyms gene name: |
Cas-Br-M (murine) ecotropic retroviral transforming sequence Cbl proto-oncogene, E3 ubiquitin protein ligase |
| Synonyms name: |
oncogene CBL2 |
| Locus: |
11q23, 3 |
| Discovery year: |
1989-06-30 |
| GenBank acession: |
X57110 |
| Entrez gene record: |
867 |
| Pubmed identfication: |
2013228 |
| RefSeq identity: |
NM_005188 |
| Classification: |
Ring finger proteins |
| Havana BLAST/BLAT: |
OTTHUMG00000166170 |
| Locus Specific Databases: |
LRG_608 |