| Long name: |
ALEXA FLUOR 350 Conjugated, ATG4D Polyclonal Antibody |
| Also known as: |
Anti-ATG4D PAb ALEXA FLUOR 350 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
350, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
ATG4D |
| Specificity: |
This is a highly specific antibody against ATG4D |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
425-474/474 |
| Subcellular location: |
Mitochondrion, Cytoplasm |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human ATG4D |
| Gene ID Number: |
84971 |
| Swiss Prot: |
Q86TL0 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3 and GABARAPL2, Cysteine protease ATG4D, Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, Has also an activity of delipidating enzyme for the PE-conjugated forms, ROS, The mitochondrial import of ATG4D during cellular stress and differentiation may play important roles in the regulation of mitochondrial physiology, mitochondrial: Plays a role as an autophagy regulator that links mitochondrial dysfunction with apoptosis, mitophagy and cell viability, to reveal a C-terminal glycine, which is necessary for autophagy, Cysteine protease ATG4D: Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
343nm/442nm |
| Synonyms: |
APG4-D |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 350, Alexa Fluor |
| Gene target: |
ATG4D |
| Short name: |
ATG4D Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 350 |
| Alternative name: |
ALEXA FLUOR 350, ATG4D (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
20789 |
| Gene: |
ATG4D |
More about : ATG4D |
| Long gene name: |
autophagy related 4D cysteine peptidase |
| Synonyms gene: |
AUTL4 APG4D |
| Synonyms gene name: |
AUT-like 4, cerevisiae) APG4 autophagy 4 homolog D (S, cerevisiae) ATG4 autophagy related 4 homolog D (S, cerevisiae) autophagy related 4D, cysteine endopeptidase (S, cysteine peptidase |
| Locus: |
19p13, 2 |
| Discovery year: |
2003-04-11 |
| GenBank acession: |
AJ312332 |
| Entrez gene record: |
84971 |
| Pubmed identfication: |
12446702 |
| RefSeq identity: |
NM_032885 |
| Classification: |
Autophagy related |
| Havana BLAST/BLAT: |
OTTHUMG00000180582 |