| Long name: |
Cubilin Primary Polyclonal Antibody |
| Also known as: |
Cubilin PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
Cubilin |
| Specificity: |
This is a highly specific antibody against Cubilin |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
50-90/3623 |
| Subcellular location: |
Intracellular |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Cubilin |
| Gene ID number: |
8029 |
| Swiss Prot: |
O60494 |
| Tested Applications: |
IF(IHC-P), IHC-P |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
ALB, APOA1, Binds to ALB, Binds to LGALS3 at the maternal-fetal interface, GC, Interaction with AMN controls its trafficking to the plasma membrane and facilitates endocytosis of ligands, Interaction with LRP2 mediates its trafficking throughout vesicles and facilitates the uptake of specific ligands like GC, Kappa and lambda-light chains, MB, May play an important role in the development of the peri-implantation embryo through internalization of APOA1 and cholesterol, SCGB1A1, Serves as important transporter in several absorptive epithelia, TF, TF and SCGB1A1, The binding of all ligands requires calcium, and the GIF-cobalamin complex, by facilitating their uptake, hemoglobin, hemoglobin, high density lipoprotein, including intestine, renal proximal tubules and embryonic yolk sac, vitamin and iron metabolism, Cotransporter which plays a role in lipoprotein |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
460 kDa receptor, CUBN, Cubilin, Intestinal intrinsic factor receptor, Intrinsic factor-cobalamin receptor, Intrinsic factor-vitamin B12 receptor, MGA1, gp280, IFCR |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
Cubilin |
| Short name: |
Cubilin Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
Cubilin (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
44984 |
| Gene: |
CUBNP2 |
More about : CUBNP2 |
| Long gene name: |
cubilin pseudogene 2 |
| Synonyms gene name: |
cubilin (intrinsic factor-cobalamin receptor) pseudogene 2 |
| Locus: |
10q11, 21 |
| Discovery year: |
2013-01-03 |
| Entrez gene record: |
100289280 |
| Havana BLAST/BLAT: |
OTTHUMG00000018078 |