| Long name: |
GPX4 Primary Polyclonal Antibody |
| Also known as: |
GPX4 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
GPX4 |
| Specificity: |
This is a highly specific antibody against GPX4 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Glutathione Peroxidase 4 |
| Gene ID number: |
2879 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
All mammalian GPx family members, Extracellular plasma GPx (pGPx or GPx3) is mainly expressed by the kidney from where it is released into the blood circulation, GPx2, Phospholipid hydroperoxide GPx4 (PH-GPx) expressed in most tissues, The classical cytosolic/mitochondrial GPx1 (cGPx) is a selenium-dependent enzyme, There are several isoforms which differ in their primary structure and localization, also known as gastrointestinal GPx (GI-GPx), can reduce many hydroperoxides including hydroperoxides integrated in membranes, except for the recently described Cys containing GPx3 and epididymis-specific secretory GPx (eGPx or GPx5) isoforms, first of the GPx family to be discovered, hydroperoxy lipids in low density lipoprotein or thymine, is an intracellular enzyme expressed only at the epithelium of the gastrointestinal tract, possess selenocysteine at the active site, Glutathione peroxidases (Gpxs) are ubiquitously expressed proteins which catalyze the reduction of hydrogen peroxides and organic hydroperoxides by glutathione |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
GPX 4, GPX-4, GPX4, GPX4_HUMAN, GSHPx-4, MCSP, PHGPx, Phospholipid hydroperoxidase, Phospholipid hydroperoxide glutathione peroxidase, Phospholipid hydroperoxide glutathione peroxidase, Phospholipid hydroperoxide glutathione peroxidase mitochondrial, Sperm nucleus glutathione peroxidase, mitochondrial, snGPx, snPHGPx, Glutathione peroxidase 4 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
GPX4 |
| Short name: |
GPX4 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
GPX4 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
4556 |
| Gene: |
GPX4 |
More about : GPX4 |
| Long gene name: |
glutathione peroxidase 4 |
| Synonyms gene name: |
glutathione peroxidase 4 (phospholipid hydroperoxidase) |
| Synonyms: |
PHGPx MCSP |
| Synonyms name: |
phospholipid hydroperoxidase |
| Locus: |
19p13, 3 |
| Discovery year: |
1993-05-03 |
| GenBank acession: |
BC039849 X71973 |
| Entrez gene record: |
2879 |
| Pubmed identfication: |
8287691 8039723 10464096 |
| RefSeq identity: |
NM_002085 |
| Classification: |
Selenoproteins |
| Havana BLAST/BLAT: |
OTTHUMG00000181874 |