| Long name: |
Acetyl-Histone H3(K23) Antibody |
| Also known as: |
Acetyl-Histone H3(K23) Antibody |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
Acetyl-Histone H3K23 |
| Specificity: |
This acetylation site is homologous across the species listed, This is a highly specific antibody against Acetyl-Histone H3K23 |
| Modification(s): |
Acetylation |
| Modification site(s): |
K23 |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
10-40/136 |
| Subcellular location: |
Nucleus |
| Source: |
KLH conjugated synthetic acetylpeptide derived from human Histone H3 around acetylation site of Lys23 |
| Gene ID number: |
3020 |
| Swiss Prot: |
P84243 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Constitutes the predominant form of histone H3 in non-dividing cells and is incorporated into chromatin independently of DNA synthesis, DNA accessibility is regulated via a complex set of post-translational modifications of histones, DNA repair, DNA replication and chromosomal stability, Deposited at sites of nucleosomal displacement throughout transcribed genes, Histones thereby play a central role in transcription regulation, Nucleosomes wrap and compact DNA into chromatin, also called histone code, and nucleosome remodeling, limiting DNA accessibility to the cellular machineries which require DNA as a template, suggesting that it represents an epigenetic imprint of transcriptionally active chromatin, Variant histone H3 which replaces conventional H3 in a wide range of nucleosomes in active genes |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
H3, H3F3A, Histone H3, PP781, 3, 3A, H3F3 |
| Description: |
N terminal acetylation or CH3CO as epigenetic regulation of -Histone H3(K23) Antibody by NATs |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
Histone H3(K23) |
| Short name: |
-Histone H3(K23) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
Acetyl-Histone H3(K23) (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
6438 |
| Gene: |
KRT23 |
More about : KRT23 |
| Long gene name: |
keratin 23 |
| Synonyms gene name: |
keratin 23 (histone deacetylase inducible) keratin 23, type I |
| Synonyms: |
K23 DKFZP434G032 HAIK1 CK23 MGC26158 |
| Locus: |
17q21, 2 |
| Discovery year: |
2000-07-31 |
| GenBank acession: |
AF102848 |
| Entrez gene record: |
25984 |
| Pubmed identfication: |
11135429 16831889 |
| Classification: |
Keratins, type I |
| Havana BLAST/BLAT: |
OTTHUMG00000133376 |