| Long name: |
Cystatin C/CST3 Primary Polyclonal Antibody |
| Also known as: |
Cystatin C/CST3 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
Cystatin C/CST3 |
| Specificity: |
This is a highly specific antibody against Cystatin C/CST3 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from mouse Cystatin 3 |
| Gene ID number: |
1471 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
A mutation in this gene has been associated with amyloid angiopathy, Expression of this protein in vascular wall smooth muscle cells is severely reduced in both atherosclerotic and aneurysmal aortic lesions, Some of the members are active cysteine protease inhibitors, The cystatin locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes, The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions, There are three inhibitory families in the superfamily, This gene is located in the cystatin locus and encodes the most abundant extracellular inhibitor of cysteine proteases, [provided by RefSeq], establishing its role in vascular disease, including the type 1 cystatins(stefins), type 2 cystatins and the kininogens, where they appear to provide protective functions, which is found in high concentrations in biological fluids and is expressed in virtually all organs of the body, while others have lost or perhaps never acquired this inhibitory activity, The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
AD 8, AD8, ARMD11, Amyloid angiopathy and cerebral hemorrhage, CST 3, CST-3, CST3 protein, Cst 3, Cst3, Cystatin 3, Cystatin C, Cystatin-3, Cystatin3, CystatinC, Gamma trace, HCCAA, MGC117328, Neuroendocrine basic polypeptide, Post gamma globulin, CST3, Cystatin 3 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
Cystatin C/CST3 |
| Short name: |
Cystatin C/CST3 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
Cystatin C/CST3 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
2475 |
| Gene: |
CST3 |
More about : CST3 |
| Long gene name: |
cystatin C |
| Synonyms gene name: |
cystatin C (amyloid angiopathy and cerebral hemorrhage) |
| Locus: |
20p11, 21 |
| Discovery year: |
1990-02-06 |
| Entrez gene record: |
1471 |
| Pubmed identfication: |
8486384 |
| RefSeq identity: |
NM_000099 |
| Classification: |
Cystatins, type 2 |
| Havana BLAST/BLAT: |
OTTHUMG00000032080 |