| Long name: |
Tyk2 Primary Polyclonal Antibody |
| Also known as: |
Tyk2 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
Tyk2 |
| Specificity: |
This is a highly specific antibody against Tyk2 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Tyk2 |
| Gene ID number: |
7297 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E, As such, It is also component of both the type I and type III interferon signaling pathways, This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits, [provided by RefSeq], it may play a role in anti-viral immunity, more specifically, the Janus kinases (JAKs) protein families, This gene encodes a member of the tyrosine kinase and |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
JTK1, Non receptor tyrosine protein kinase 2, Non receptor tyrosine protein kinase TYK2, Non-receptor tyrosine-protein kinase TYK2, Protein Tyrosine Kinase 2, TYK 2, TYK2_HUMAN, Tyrosine kinase 2, JTK 1 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
Tyk2 |
| Short name: |
Tyk2 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
tyrosine kinase 2 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
12440 |
| Gene: |
TYK2 |
More about : TYK2 |
| Long gene name: |
tyrosine kinase 2 |
| Synonyms: |
JTK1 |
| Locus: |
19p13, 2 |
| Discovery year: |
1990-09-10 |
| Entrez gene record: |
7297 |
| Pubmed identfication: |
2156206 |
| Classification: |
FERM domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000166373 |
| Locus Specific Databases: |
TYK2base: Mutation registry for TYK2 deficiency LRG_121 |