| Long name: |
TIF1 gamma Primary Polyclonal Antibody |
| Also known as: |
TIF1 gamma PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
T1 gamma |
| Specificity: |
This is a highly specific antibody against T1 gamma |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
980-1030/1127 |
| Subcellular location: |
Nucleus |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human TIF1 gamma |
| Gene ID number: |
51592 |
| Swiss Prot: |
Q9UPN9 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
According to PubMed:16751102, Inhibits the transcriptional response to TGF-beta/BMP signaling cascade, Its association with SMAD2 and SMAD3 stimulates erythroid differentiation of hematopoietic stem/progenitor (By similarity), May act as a transcriptional repressor, Monoubiquitinates SMAD4 and acts as an inhibitor of SMAD4-dependent TGF-beta/BMP signaling cascade (Monoubiquitination of SMAD4 hampers its ability to form a stable complex with activated SMAD2/3 resulting in inhibition of TGF-beta/BMP signaling cascade), Plays a role in the control of cell proliferation, Promotes SMAD4 ubiquitination, does not promote a decrease in the level of endogenous SMAD4, nuclear exclusion and degradation via the ubiquitin proteasome pathway, Acts as an E3 ubiquitin-protein ligase |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
E3 ubiquitin-protein ligase TRIM33, Ectodermin homolog, KIAA1113, PTC7, Protein Rfg7, RET-fused gene 7 protein, RFG7, TF1G, TIF1-gamma, TIF1G, TIF1GAMMA, TIFGAMMA, TRIM33, Transcription intermediary factor 1-gamma, Tripartite motif-containing protein 33, ECTO |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
TIF1 gamma |
| Short name: |
TIF1 gamma Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
TIF1 g (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
11812 |
| Gene: |
TRIM24 |
More about : TRIM24 |
| Long gene name: |
tripartite motif containing 24 |
| Synonyms gene: |
TIF1 |
| Synonyms gene name: |
transcriptional intermediary factor 1 tripartite motif-containing 24 |
| Synonyms: |
hTIF1 Tif1a RNF82 TIF1A |
| Locus: |
7q33-q34 |
| Discovery year: |
1998-12-18 |
| GenBank acession: |
AF009353 |
| Entrez gene record: |
8805 |
| Pubmed identfication: |
9115274 9191165 |
| RefSeq identity: |
NM_015905 |
| Classification: |
Tripartite motif containing PHD finger proteins Ring finger proteins |
| Havana BLAST/BLAT: |
OTTHUMG00000155820 |