| Long name: |
Biotin Conjugated, RCC1 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
RCC1 |
| Specificity: |
This is a highly specific antibody against RCC1 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
2-50/421 |
| Subcellular location: |
Nucleus, Cytoplasm |
| Source: |
KLH conjugated synthetic peptide derived from human RCC1 |
| Gene ID number: |
1104 |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
RCC1, RanGTP localization has been proposed to result from the association of Ran's GDP/GTP exchange factor, The latter functions rely on the presence of high local concentrations of GTP bound Ran near mitotic chromatin, and, but Ran is shown here to bind directly to chromatin in two modes, either dependent or independent of RCC1, to increase the affinity of chromatin for NE membranes, where bound, with chromatin , Ran GTPase plays important roles in nucleocytoplasmic transport in interphase and in both spindle formation and nuclear envelope (NE) assembly during mitosis |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
RCC1 Conjugated |
| Short name: |
Conjugated, RCC1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
biotinilated coupled, RCC1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
1913 |
| Gene: |
RCC1 |
More about : RCC1 |
| Long gene name: |
regulator of chromosome condensation 1 |
| Synonyms gene: |
CHC1 |
| Synonyms gene name: |
chromosome condensation 1 |
| Locus: |
1p35, 3 |
| Discovery year: |
1986-01-01 |
| GenBank acession: |
X12654 |
| Entrez gene record: |
1104 |
| Pubmed identfication: |
7851910 |
| RefSeq identity: |
NM_001269 |
| Havana BLAST/BLAT: |
OTTHUMG00000003645 |